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| Open AccessNetwork pharmacology analysis and experimental validation to explore the mechanism of kaempferol in the treatment of osteoporosis
- Qi Dong
- , Guoxia Ren
- & Dingjun Hao
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| Open AccessTranscriptomic screening of novel targets of sericin in human hepatocellular carcinoma cells
- Jiraporn Jantaravinid
- , Napatara Tirawanchai
- & Pornanong Aramwit
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| Open AccessAcute kidney injury interacts with VKORC1 genotype on initiative warfarin dose among heart surgery recipients: a real-world research
- Liang Xiong
- , Feng Yu
- & Hang Xu
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| Open AccessA cell-based assay for rapid assessment of ACE2 catalytic function
- Warren M. Meyers
- , Ryan J. Hong
- & Kurt Haas
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| Open AccessMolecular basis of GDF15 induction and suppression by drugs in cardiomyocytes and cancer cells toward precision medicine
- Lisa-Maria Winter
- , Diana Reinhardt
- & Seong-Wook Yun
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| Open AccessConstitutive androstane receptor and pregnane X receptor genotype influence efavirenz plasma concentration and CYP2B6 enzyme activity
- Zelalem Petros
- , Abiy Habtewold
- & Eleni Aklillu
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| Open AccessGenome-wide pharmacogenetics of anti-drug antibody response to bococizumab highlights key residues in HLA DRB1 and DQB1
- Daniel I. Chasman
- , Craig L. Hyde
- & A. Katrina Loomis
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| Open AccessThe effect of renin–angiotensin–aldosterone system inhibitors on organ-specific ace2 expression in zebrafish and its implications for COVID-19
- Gha-hyun J. Kim
- , Adam Melgoza
- & Su Guo
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| Open AccessA multicenter case–control study of the effect of e-nos VNTR polymorphism on upper gastrointestinal hemorrhage in NSAID users
- Narmeen Mallah
- , Maruxa Zapata-Cachafeiro
- & Adolfo Figueiras
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| Open AccessGenetic influence of CYP2D6 on pharmacokinetics and acute subjective effects of LSD in a pooled analysis
- Patrick Vizeli
- , Isabelle Straumann
- & Matthias E. Liechti
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| Open AccessEffect of four ABCB1 genetic polymorphisms on the accumulation of darunavir in HEK293 recombinant cell lines
- Gabriel Stillemans
- , Happy Phanio Djokoto
- & Laure Elens
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| Open AccessEarly impact of donor CYP3A5 genotype and Graft-to-Recipient Weight Ratio on tacrolimus pharmacokinetics in pediatric liver transplant patients
- Michele Pinon
- , Amedeo De Nicolò
- & Pier Luigi Calvo
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| Open AccessModulation of CYP2C9 activity and hydrogen peroxide production by cytochrome b5
- Javier Gómez-Tabales
- , Elena García-Martín
- & Carlos Gutierrez-Merino
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| Open AccessCombinations of common SNPs of the transporter gene ABCB1 influence apparent bioavailability, but not renal elimination of oral digoxin
- Chih-hsuan Hsin
- , Marc S. Stoffel
- & Max Taubert
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| Open AccessHuman essential hypertension: no significant association of polygenic risk scores with antihypertensive drug responses
- Heini Sánez Tähtisalo
- , Sanni Ruotsalainen
- & Timo P. Hiltunen
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| Open AccessPharmacogenomics of poor drug metabolism in Greyhounds: Cytochrome P450 (CYP) 2B11 genetic variation, breed distribution, and functional characterization
- Stephanie E. Martinez
- , Marie C. Andresen
- & Michael H. Court
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| Open AccessImpact of methylenetetrahydrofolate reductase C677T polymorphism on the efficacy of photodynamic therapy in patients with neovascular age-related macular degeneration
- Francesco Parmeggiani
- , Carla Enrica Gallenga
- & Francesco Saverio Sorrentino
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| Open AccessExtracts of Qizhu decoction inhibit hepatitis and hepatocellular carcinoma in vitro and in C57BL/6 mice by suppressing NF-κB signaling
- Ling-feng Wan
- , Jian-jiang Shen
- & Bo-yu Xue
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| Open AccessOATP1B3 (699G>A) and CYP2C9*2, *3 significantly influenced the transport and metabolism of glibenclamide and glipizide
- Fayou Yang
- , Linlin Liu
- & Chunhua Xia
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| Open AccessLong-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype
- Eliford Ngaimisi Kitabi
- , Omary Mashiku Sylivester Minzi
- & Eleni Aklillu
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| Open AccessThe effect of Ganoderma lucidum extract on immunological function and identify its anti-tumor immunostimulatory activity based on the biological network
- Ruolin Zhao
- , Qilong Chen
- & Yu-min He
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| Open AccessPhysiologically based pharmacokinetic modelling of atomoxetine with regard to CYP2D6 genotypes
- Se-Hyung Kim
- , Ji-Young Byeon
- & Seok-Yong Lee
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| Open AccessCYP2C9 and OATP1B1 genetic polymorphisms affect the metabolism and transport of glimepiride and gliclazide
- Fayou Yang
- , Xiaomin Xiong
- & Chunhua Xia
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| Open AccessEffect of ABCB1 genetic polymorphisms on the transport of rivaroxaban in HEK293 recombinant cell lines
- Anne-Laure Sennesael
- , Nadtha Panin
- & Laure Elens
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| Open AccessComparative analysis of xenobiotic metabolising N-acetyltransferases from ten non-human primates as in vitro models of human homologues
- Theodora Tsirka
- , Maria Konstantopoulou
- & Giannoulis Fakis
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| Open AccessUse of quercetin in animal feed: effects on the P-gp expression and pharmacokinetics of orally administrated enrofloxacin in chicken
- Zohaib Ahmed Bhutto
- , Fang He
- & Liping Wang
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| Open AccessCharacterising the nicotine metabolite ratio and its association with treatment choice: A cross sectional analysis of Stop Smoking Services in England
- Lion Shahab
- , Emily Mortimer
- & Rachel F. Tyndale
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| Open AccessPrediction of plasma efavirenz concentrations among HIV-positive patients taking efavirenz-containing combination antiretroviral therapy
- Sung-Hsi Huang
- , Shu-Wen Lin
- & Shan-Chwen Chang
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| Open AccessA chalcone derivative reactivates latent HIV-1 transcription through activating P-TEFb and promoting Tat-SEC interaction on viral promoter
- Jun Wu
- , Ming-tao Ao
- & Yu-hua Xue
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| Open AccessGLCCI1 rs37973: a potential genetic predictor of therapeutic response to inhaled corticosteroids in Chinese chronic obstructive pulmonary disease patients
- Yuan Lei
- , Yiping Gao
- & Jungang Xie
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| Open AccessA Chinese herbal decoction, reformulated from Kai-Xin-San, relieves the depression-like symptoms in stressed rats and induces neurogenesis in cultured neurons
- Lu Yan
- , Qinghua Hu
- & Karl W. K. Tsim
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| Open AccessIntegrative analysis of cancer genes in a functional interactome
- Matthew H. Ung
- , Chun-Chi Liu
- & Chao Cheng
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| Open AccessThe independent contribution of miRNAs to the missing heritability in CYP3A4/5 functionality and the metabolism of atorvastatin
- Ju-E Liu
- , Bin Ren
- & Shi-Long Zhong
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| Open AccessQuantitative proteomics study of the neuroprotective effects of B12 on hydrogen peroxide-induced apoptosis in SH-SY5Y cells
- Lijun Zhong
- , Juntuo Zhou
- & Yan Pan
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| Open AccessExtraction, purification and anti-fatigue activity of γ-aminobutyric acid from mulberry (Morus alba L.) leaves
- Hengwen Chen
- , Xuanhui He
- & Jie Wang
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| Open AccessPretreatment with β-Boswellic Acid Improves Blood Stasis Induced Endothelial Dysfunction: Role of eNOS Activation
- Mingming Wang
- , Minchun Chen
- & Aidong Wen
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| Open AccessGeneration of a Homozygous Transgenic Rat Strain Stably Expressing a Calcium Sensor Protein for Direct Examination of Calcium Signaling
- Kornélia Szebényi
- , András Füredi
- & Tamás I. Orbán
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| Open AccessThe Effect of microRNAs in the Regulation of Human CYP3A4: a Systematic Study using a Mathematical Model
- Zhiyun Wei
- , Songshan Jiang
- & Qinghe Xing
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| Open AccessGalantamine improves olfactory learning in the Ts65Dn mouse model of Down syndrome
- Fabio M. Simoes de Souza
- , Nicolas Busquet
- & Diego Restrepo