Natural product synthesis articles within Scientific Reports

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• Article
  18 November 2023 | Open Access

  Computational analysis and experimental verification of donor–acceptor behaviour of berberine, and its co-oligomers and co-polymers with ethylenedıoxythıophene

  • R. M. Gamini Rajapakse
  • , Benjamin R. Horrocks
  •  & Chandana P. Udawatte

• Article
  24 October 2023 | Open Access

  Synergistic performance of a new bimetallic complex supported on magnetic nanoparticles for Sonogashira and C–N coupling reactions

  • Fatemeh Nasseri
  • , Mohammad Ali Nasseri
  •  & Issa Yavari

• Article
  25 September 2023 | Open Access

  Generation of potent antibacterial compounds through enzymatic and chemical modifications of the trans-δ-viniferin scaffold

  • Robin Huber
  • , Laurence Marcourt
  •  & Emerson Ferreira Queiroz

• Article
  22 May 2023 | Open Access

  Solid acid-catalyzed one-step synthesis of oleacein from oleuropein

  • Yasuhiro Shimamoto
  • , Tadahiro Fujitani
  •  & Ken-ichi Tominaga

• Article
  30 January 2023 | Open Access

  Truncated ring-A amaryllidaceae alkaloid modulates the host cell integrated stress response, exhibiting antiviral activity to HSV-1 and SARSCoV-2

  • James McNulty
  • , Chanti Babu-Dokuburra
  •  & Leonardo D’Aiuto

• Article
  29 August 2022 | Open Access

  Inhibitory effects of Serjania erecta on the development of Chrysodeixis includens

  • Samylla Tassia Ferreira de Freitas
  • , Agna Rita dos Santos Rodrigues
  •  & Fábio Henrique Dyszy

• Article
  15 June 2022 | Open Access

  Molecular-docking-guided design, palladium-catalyzed synthesis and anticancer activity of paclitaxel-benzoxazoles hybrids

  • Ting Jiang
  • , Ya-Nan Cao
  •  & Ling-Li Zheng

• Article
  16 May 2022 | Open Access

  Decoration of green synthesized S, N-GQDs and CoFe₂O₄ on halloysite nanoclay as natural substrate for electrochemical hydrogen storage application

  • Maryam Ghiyasiyan-Arani
  •  & Masoud Salavati-Niasari

• Article
  06 May 2022 | Open Access

  Total synthesis and antimicrobial evaluation of (+)-hygrophorone B¹² and its analogues

  • Takaaki Kamishima
  • , Masato Suzuki
  •  & Hitoshi Kasai

• Article
  16 March 2022 | Open Access

  A new feed additive composed of urea and soluble carbohydrate coated with wax for controlled release in ruminal fluid

  • Alexandre Guimarães Inácio
  • , Camila Celeste Brandão Ferreira Ítavo
  •  & Luís Carlos Vinhas Ítavo

• Article
  15 December 2021 | Open Access

  Chemoselectivity-independent Cu-mediated coupling to construct the hydroquinoline skeleton of symbioimine

  • Rie Fujita
  • , Kengo Hanaya
  •  & Shuhei Higashibayashi

• Article
  07 October 2021 | Open Access

  Total synthesis of (±)-decursivine via BINOL-phosphoric acid catalyzed tandem oxidative cyclization

  • Prakash T. Parvatkar
  • , Eugene S. Smotkin
  •  & Roman Manetsch

• Article
  05 August 2021 | Open Access

  Structure elucidation of the novel carotenoid gemmatoxanthin from the photosynthetic complex of Gemmatimonas phototrophica AP64

  • Nupur
  • , Marek Kuzma
  •  & Michal Koblížek

• Article
  17 February 2021 | Open Access

  Insecticidal and oviposition deterrent effects of essential oils of Baccharis spp. and histological assessment against Drosophila suzukii (Diptera: Drosophilidae)

  • Michele Trombin de Souza
  • , Mireli Trombin de Souza
  •  & Maria Aparecida Cassilha Zawadneak

• Article
  11 February 2021 | Open Access

  Identification, heterologous production and bioactivity of lentinulin A and dendrothelin A, two natural variants of backbone N-methylated peptide macrocycle omphalotin A

  • Emmanuel Matabaro
  • , Hannelore Kaspar
  •  & Markus Künzler

• Article
  21 January 2021 | Open Access

  Syntheses of dinor-cis/iso-12-oxo-phytodienoic acid (dn-cis/iso-OPDAs), ancestral jasmonate phytohormones of the bryophyte Marchantia polymorpha L., and their catabolites

  • Jianxin Wang
  • , Haruka Sakurai
  •  & Minoru Ueda

• Article
  16 December 2020 | Open Access

  Identification of a new cannabidiol n-hexyl homolog in a medicinal cannabis variety with an antinociceptive activity in mice: cannabidihexol

  • Pasquale Linciano
  • , Cinzia Citti
  •  & Giuseppe Cannazza

• Article
  08 December 2020 | Open Access

  Total synthesis of lindbladione, a Hes1 dimerization inhibitor and neural stem cell activator isolated from Lindbladia tubulina

  • Midori A. Arai
  • , Yuna Makita
  •  & Masami Ishibashi

• Article
  16 September 2020 | Open Access

  Honey isomaltose contributes to the induction of granulocyte-colony stimulating factor (G-CSF) secretion in the intestinal epithelial cells following honey heating

  • Xin Xu
  • , Koshi Asai
  •  & Toshiaki Makino

• Article
  25 March 2020 | Open Access

  Improving the drug-likeness of inspiring natural products - evaluation of the antiparasitic activity against Trypanosoma cruzi through semi-synthetic and simplified analogues of licarin A

  • Thiago R. Morais
  • , Geanne A. Alves Conserva
  •  & João Henrique G. Lago

• Article
  24 February 2020 | Open Access

  Biocarbon from peanut hulls and their green composites with biobased poly(trimethylene terephthalate) (PTT)

  • Maisyn Picard
  • , Suman Thakur
  •  & Amar K. Mohanty

• Article
  14 February 2020 | Open Access

  Novel Ocellatin Peptides Mitigate LPS-induced ROS Formation and NF-kB Activation in Microglia and Hippocampal Neurons

  • Nayara A. Sousa
  • , Guilherme A. L. Oliveira
  •  & Jand Venes R. Medeiros

• Article
  13 February 2020 | Open Access

  Pyrocatechol, a component of coffee, suppresses LPS-induced inflammatory responses by inhibiting NF-κB and activating Nrf2

  • Megumi Funakoshi-Tago
  • , Yusuke Nonaka
  •  & Hiroomi Tamura

• Article
  31 December 2019 | Open Access

  Nutraceuticals, antioxidant pigments, and phytochemicals in the leaves of Amaranthus spinosus and Amaranthus viridis weedy species

  • Umakanta Sarker
  •  & Shinya Oba

• Article
  02 December 2019 | Open Access

  Synthesis and biological activities of two camptothecin derivatives against Spodoptera exigua

  • Fulai Yang
  • , Liping Wang
  •  & Hongyun Jiang

• Article
  23 September 2019 | Open Access

  Enrichment of Eucalyptus oil nanoemulsion by micellar nanotechnology: transdermal analgesic activity using hot plate test in rats’ assay

  • Zarith Asyikin Abdul Aziz
  • , Hasmida Mohd Nasir
  •  & Ghulam Md Ashraf

• Article
  20 February 2019 | Open Access

  Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold

  • Luisa Moretto
  • , Rachel Heylen
  •  & R. William Broadhurst

• Article
  07 February 2019 | Open Access

  Defining the genes for the final steps in biosynthesis of the complex polyketide antibiotic mupirocin by Pseudomonas fluorescens NCIMB10586

  • Jack A. Connolly
  • , Amber Wilson
  •  & Christopher M. Thomas

• Article
  22 January 2019 | Open Access

  Oral crocetin administration suppressed refractive shift and axial elongation in a murine model of lens-induced myopia

  • Kiwako Mori
  • , Toshihide Kurihara
  •  & Kazuo Tsubota

• Article
  15 November 2018 | Open Access

  Insights into the Chemistry of Non-Enzymatic Browning Reactions in Different Ribose-Amino Acid Model Systems

  • Daniel Hemmler
  • , Chloé Roullier-Gall
  •  & Philippe Schmitt-Kopplin

• Article
  30 August 2018 | Open Access

  Application of the fragment molecular orbital method to discover novel natural products for prion disease

  • Jiwon Choi
  • , Hyo-Jin Kim
  •  & Hyun-Joo Sohn

• Article
  06 August 2018 | Open Access

  Novel Nanosized Chitosan-Betulinic Acid Against Resistant Leishmania Major and First Clinical Observation of such parasite in Kidney

  • Tahereh Zadeh Mehrizi
  • , Mehdi Shafiee Ardestani
  •  & Amitis Ramezani

• Article
  13 July 2018 | Open Access

  Sustainable Syntheses of (−)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site

  • Christopher J. Smedley
  • , Paul A. Stanley
  •  & John E. Moses

• Article
  13 June 2018 | Open Access

  Synthesis, antimicrobial activity and conformational analysis of the class IIa bacteriocin pediocin PA-1 and analogs thereof

  • François Bédard
  • , Riadh Hammami
  •  & Eric Biron

• Article
  31 May 2018 | Open Access

  Simultaneous purification of dihydrotanshinone, tanshinone I, cryptotanshinone, and tanshinone IIA from Salvia miltiorrhiza and their anti-inflammatory activities investigation

  • Hongwei Gao
  • , Liting Huang
  •  & Shilin Yang

• Article
  11 April 2018 | Open Access

  A Bowman-Birk type chymotrypsin inhibitor peptide from the amphibian, Hylarana erythraea

  • Luyao Zhang
  • , Xiaoling Chen
  •  & Lei Wang

• Article
  03 April 2018 | Open Access

  Acute metabolic actions of the major polyphenols in chamomile: an in vitro mechanistic study on their potential to attenuate postprandial hyperglycaemia

  • Jose A. Villa-Rodriguez
  • , Asimina Kerimi
  •  & Gary Williamson

• Article
  05 February 2018 | Open Access

  Synthesis of a multifunctional hard monomer from rosin: the relationship of allyl structure in maleopimarate and UV-curing property

  • Yanju Lu
  • , Zhendong Zhao
  •  & Shichao Xu

• Article
  18 December 2017 | Open Access

  Feed gas effect on plasma inactivation mechanism of Salmonella Typhimurium in onion and quality assessment of the treated sample

  • Muhammad Saiful Islam Khan
  • , Eun-Jung Lee
  •  & Yun-Ji Kim

• Article
  05 December 2017 | Open Access

  Total synthesis of the reported structure of 13a-hydroxytylophorine

  • Hui Zhang
  • , Gang Li
  •  & Qing-Min Wang

• Article
  06 November 2017 | Open Access

  Molecular-trapping in Emulsion’s Monolayer: A New Strategy for Production and Purification of Bioactive Saponins

  • Titus C. Obasi
  • , Radu Moldovan
  •  & Radu Oprean

• Article
  14 September 2017 | Open Access

  Synthesis and in-vitro anticancer evaluation of polyarsenicals related to the marine sponge derived Arsenicin A

  • Ines Mancini
  • , Matteo Planchestainer
  •  & Andrea Defant

• Article
  31 August 2017 | Open Access

  1α,20S-Dihydroxyvitamin D₃ Interacts with Vitamin D Receptor: Crystal Structure and Route of Chemical Synthesis

  • Zongtao Lin
  • , Hao Chen
  •  & Wei Li

• Article
  21 August 2017 | Open Access

  Phytotoxic dioxolanones are potential virulence factors in the infection process of Guignardia bidwellii

  • Iris Buckel
  • , Lars Andernach
  •  & Eckhard Thines

• Article
  10 August 2017 | Open Access

  Epicatechin oligomers longer than trimers have anti-cancer activities, but not the catechin counterparts

  • Kohki Takanashi
  • , Manato Suda
  •  & Hidefumi Makabe

• Article
  04 August 2017 | Open Access

  Identification of a male-produced sex-aggregation pheromone for a highly invasive cerambycid beetle, Aromia bungii

  • Tian Xu
  • , Hiroe Yasui
  •  & Jocelyn G. Millar

• Article
  03 August 2017 | Open Access

  Antimalarial troponoids, puberulic acid and viticolins; divergent synthesis and structure-activity relationship studies

  • Goh Sennari
  • , Ryo Saito
  •  & Toshiaki Sunazuka

• Article
  24 April 2017 | Open Access

  Synthesis and anti-obesity effects in vivo of Crotadihydrofuran C as a novel PPARγ antagonist from Crotalaria albida

  • Qin-Hu Sun
  • , Yu Zhang
  •  & Gui-Xin Chou

• Article
  11 April 2017 | Open Access

  Synthesis of Chrysogeside B from Halotolerant Fungus Penicillium and Its Antimicrobial Activities Evaluation

  • Ruiquan Liu
  • , Lei Wang
  •  & Shangzhong Liu

• Article
  28 March 2017 | Open Access

  Mining of efficient microbial UDP-glycosyltransferases by motif evolution cross plant kingdom for application in biosynthesis of salidroside

  • Bo Fan
  • , Tianyi Chen
  •  & Bingfang He