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| Open AccessFast NMR method to probe solvent accessibility and disordered regions in proteins
- André F. Faustino
- , Glauce M. Barbosa
- & Ivo C. Martins
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| Open AccessIntrinsic disorder in the regulatory N-terminal domain of diacylglycerol acyltransferase 1 from Brassica napus
- Rashmi Panigrahi
- , Tsutomu Matsui
- & M. Joanne Lemieux
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| Open AccessThe yeast GRASP Grh1 displays a high polypeptide backbone mobility along with an amyloidogenic behavior
- N. A. Fontana
- , R. Fonseca-Maldonado
- & A. J. Costa-Filho
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| Open AccessDynamics of liquid-liquid phase separation of wheat gliadins
- Adeline Boire
- , Christian Sanchez
- & Paul Menut
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| Open AccessTwo Tau binding sites on tubulin revealed by thiol-disulfide exchanges
- Marlène Martinho
- , Diane Allegro
- & Pascale Barbier
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| Open AccessInsights into the structure and dynamics of lysyl oxidase propeptide, a flexible protein with numerous partners
- Sylvain D. Vallet
- , Adriana E. Miele
- & Sylvie Ricard-Blum
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| Open AccessSteric interference from intrinsically disordered regions controls dynamin-related protein 1 self-assembly during mitochondrial fission
- Bin Lu
- , Bridget Kennedy
- & Rajesh Ramachandran
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| Open AccessThe transition state structure for binding between TAZ1 of CBP and the disordered Hif-1α CAD
- Ida Lindström
- , Eva Andersson
- & Jakob Dogan
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| Open AccessStructural characteristics and membrane interactions of tandem α-synuclein oligomers
- Chunhua Dong
- , Marion Hoffmann
- & Michael T. Woodside
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| Open AccessStructural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β
- Joseph W. Arndt
- , Fang Qian
- & Paul H. Weinreb
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| Open AccessDeciphering the dark proteome of Chikungunya virus
- Ankur Singh
- , Ankur Kumar
- & Rajanish Giri
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| Open AccessAbundant fish protein inhibits α-synuclein amyloid formation
- Tony Werner
- , Ranjeet Kumar
- & Pernilla Wittung-Stafshede
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| Open AccessSmall Molecules Attenuate the Interplay between Conformational Fluctuations, Early Oligomerization and Amyloidosis of Alpha Synuclein
- Sumanta Ghosh
- , Amrita Kundu
- & Krishnananda Chattopadhyay
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| Open AccessZinc ion rapidly induces toxic, off-pathway amyloid-β oligomers distinct from amyloid-β derived diffusible ligands in Alzheimer’s disease
- Ming-Che Lee
- , Wan-Cheng Yu
- & Yun-Ru Chen
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| Open AccessPlastic roles of phenylalanine and tyrosine residues of TLS/FUS in complex formation with the G-quadruplexes of telomeric DNA and TERRA
- Keiko Kondo
- , Tsukasa Mashima
- & Masato Katahira
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| Open AccessThe intrinsically disordered Tarp protein from chlamydia binds actin with a partially preformed helix
- James Tolchard
- , Samuel J. Walpole
- & Tharin M. A. Blumenschein
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| Open AccessEpigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice
- Andras Franko
- , Diana C. Rodriguez Camargo
- & Martin Hrabě de Angelis
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| Open AccessRecognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V
- Sarah C. Atkinson
- , Michelle D. Audsley
- & Natalie A. Borg
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| Open AccessDisulfide driven folding for a conditionally disordered protein
- Hugo Fraga
- , Jordi Pujols
- & Salvador Ventura
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Article
| Open AccessThe repeat region of cortactin is intrinsically disordered in solution
- Xiaofeng Li
- , Yeqing Tao
- & Titus J. Boggon
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| Open AccessStructural disorder and induced folding within two cereal, ABA stress and ripening (ASR) proteins
- Karama Hamdi
- , Edoardo Salladini
- & Sonia Longhi
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| Open AccessThe photocycle of orange carotenoid protein conceals distinct intermediates and asynchronous changes in the carotenoid and protein components
- E. G. Maksimov
- , N. N. Sluchanko
- & A. B. Rubin
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| Open AccessRandom protein sequences can form defined secondary structures and are well-tolerated in vivo
- Vyacheslav Tretyachenko
- , Jiří Vymětal
- & Klára Hlouchová
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| Open AccessStructural dissection of human metapneumovirus phosphoprotein using small angle x-ray scattering
- Max Renner
- , Guido C. Paesen
- & Cédric Leyrat
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| Open AccessUsing chirality to probe the conformational dynamics and assembly of intrinsically disordered amyloid proteins
- Jevgenij A. Raskatov
- & David B. Teplow
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| Open AccessEmergence of Alternative Structures in Amyloid Beta 1-42 Monomeric Landscape by N-terminal Hexapeptide Amyloid Inhibitors
- Srirupa Chakraborty
- & Payel Das
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| Open AccessNon-uniform self-assembly: On the anisotropic architecture of α-synuclein supra-fibrillar aggregates
- Slav A. Semerdzhiev
- , Volodymyr V. Shvadchak
- & Mireille M. A. E. Claessens
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| Open AccessTrimethylamine N-oxide abolishes the chaperone activity of α-casein: an intrinsically disordered protein
- Mohd Younus Bhat
- , Laishram Rajendrakumar Singh
- & Tanveer Ali Dar
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| Open AccessThe relationship between folding and activity in UreG, an intrinsically disordered enzyme
- Marta Palombo
- , Alessio Bonucci
- & Barbara Zambelli
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| Open AccessIn vivo analysis of protein crowding within the nuclear pore complex in interphase and mitosis
- Hide A. Konishi
- , Suguru Asai
- & Shige H. Yoshimura
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| Open AccessStructural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7
- Danielle C. Desravines
- , Itziar Serna Martin
- & Darren J. Hart
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| Open AccessCharacterization of long and stable de novo single alpha-helix domains provides novel insight into their stability
- Marcin Wolny
- , Matthew Batchelor
- & Michelle Peckham
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Article
| Open AccessMembrane targeting of TIRAP is negatively regulated by phosphorylation in its phosphoinositide-binding motif
- Xiaolin Zhao
- , Wen Xiong
- & Daniel G. S. Capelluto
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| Open AccessThe propensity of the bacterial rodlin protein RdlB to form amyloid fibrils determines its function in Streptomyces coelicolor
- Wen Yang
- , Joost Willemse
- & Sarah Perrett
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| Open AccessRepurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species
- Florencia González-Lizárraga
- , Sergio B. Socías
- & Rosana N. Chehín
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| Open AccessThe intervening domain from MeCP2 enhances the DNA affinity of the methyl binding domain and provides an independent DNA interaction site
- Rafael Claveria-Gimeno
- , Pilar M. Lanuza
- & Adrian Velazquez-Campoy
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| Open AccessExploring the dark foldable proteome by considering hydrophobic amino acids topology
- Tristan Bitard-Feildel
- & Isabelle Callebaut
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| Open AccessEvidence for Intramolecular Antiparallel Beta-Sheet Structure in Alpha-Synuclein Fibrils from a Combination of Two-Dimensional Infrared Spectroscopy and Atomic Force Microscopy
- Steven J. Roeters
- , Aditya Iyer
- & Sander Woutersen
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| Open AccessHigh resolution spectroscopy reveals fibrillation inhibition pathways of insulin
- Tanja Deckert-Gaudig
- & Volker Deckert
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| Open AccessStructural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core
- Guilherme A. P. de Oliveira
- , Mayra de A. Marques
- & Jerson L. Silva
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| Open Accessβ-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces
- James W. P. Brown
- , Alexander K. Buell
- & Céline Galvagnion
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| Open Accessβ-Hairpin of Islet Amyloid Polypeptide Bound to an Aggregation Inhibitor
- Ewa A. Mirecka
- , Sophie Feuerstein
- & Wolfgang Hoyer
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| Open AccessThe BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation
- Tim Schulte
- , Cecilia Mikaelsson
- & Adnane Achour
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| Open AccessIndividual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells
- Anna Drews
- , Jennie Flint
- & David Klenerman
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| Open AccessThe number of α-synuclein proteins per vesicle gives insights into its physiological function
- Mohammad A. A. Fakhree
- , Niels Zijlstra
- & Mireille M. A. E. Claessens
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| Open AccessNew structural insights into Golgi Reassembly and Stacking Protein (GRASP) in solution
- Luís F. S. Mendes
- , Assuero F. Garcia
- & Antonio J. Costa-Filho
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| Open AccessA Structure-free Method for Quantifying Conformational Flexibility in proteins
- Virginia M. Burger
- , Daniel J. Arenas
- & Collin M. Stultz
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Article
| Open AccessSolution structure of the isolated histone H2A-H2B heterodimer
- Yoshihito Moriwaki
- , Tsutomu Yamane
- & Yoshifumi Nishimura
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| Open AccessTick receptor for outer surface protein A from Ixodes ricinus — the first intrinsically disordered protein involved in vector-microbe recognition
- Anna Urbanowicz
- , Dominik Lewandowski
- & Marek Figlerowicz