Featured
-
-
Article
| Open Access
Knockdown of mechanosensitive adaptor Hic-5 ameliorates post-traumatic osteoarthritis in rats through repression of MMP-13
- Aya Miyauchi
- , Masahito Noguchi
- & Joo-ri Kim-Kaneyama
-
Article
| Open Access
Polarity and mixed-mode oscillations may underlie different patterns of cellular migration
- Lucie Plazen
- , Jalal Al Rahbani
- & Anmar Khadra
-
Article
| Open Access
Proteasomal turnover of the RhoGAP tumor suppressor DLC1 is regulated by HECTD1 and USP7
- Yannick Frey
- , Mirita Franz-Wachtel
- & Monilola A. Olayioye
-
Article
| Open Access
Desmoglein-2 harnesses a PDZ-GEF2/Rap1 signaling axis to control cell spreading and focal adhesions independent of cell–cell adhesion
- W. Tucker Shelton
- , S. Madison Thomas
- & Adi D. Dubash
-
Article
| Open Access
Single molecule network analysis identifies structural changes to caveolae and scaffolds due to mutation of the caveolin-1 scaffolding domain
- Timothy H. Wong
- , Ismail M. Khater
- & Ivan R. Nabi
-
Article
| Open Access
Proline-rich tyrosine kinase 2 mediates transforming growth factor-beta-induced hepatic stellate cell activation and liver fibrosis
- Jonghwa Kim
- , Wonseok Kang
- & Yong-Han Paik
-
Article
| Open Access
Vinculins interaction with talin is essential for mammary epithelial differentiation
- Pengbo Wang
- , Jian Wu
- & Charles H. Streuli
-
Article
| Open Access
Integrin α11 cytoplasmic tail is required for FAK activation to initiate 3D cell invasion and ERK-mediated cell proliferation
- Pugazendhi Erusappan
- , Jahedul Alam
- & Donald Gullberg
-
Article
| Open Access
A novel 3D nanofibre scaffold conserves the plasticity of glioblastoma stem cell invasion by regulating galectin-3 and integrin-β1 expression
- Ali Saleh
- , Emilie Marhuenda
- & Norbert Bakalara
-
Article
| Open Access
Non-cytotoxic hydroxyl-functionalized exfoliated boron nitride nanoflakes impair the immunological function of insect haemocytes in vivo
- Elżbieta Czarniewska
- , Lucyna Mrówczyńska
- & Ewa Mijowska
-
Article
| Open Access
The ERC1 scaffold protein implicated in cell motility drives the assembly of a liquid phase
- Kristyna Sala
- , Agnese Corbetta
- & Ivan de Curtis
-
Article
| Open Access
The expression of cerebrospinal fluid exosomal miR-630 plays an important role in the dysfunction of endothelial cells after subarachnoid hemorrhage
- Leitao Sun
- , Wensheng Zhang
- & Xiaohong Wang
-
Article
| Open Access
Paxillin S273 Phosphorylation Regulates Adhesion Dynamics and Cell Migration through a Common Protein Complex with PAK1 and βPIX
- Abira Rajah
- , Colton G. Boudreau
- & Claire M. Brown
-
Article
| Open Access
Dynamics and distribution of paxillin, vinculin, zyxin and VASP depend on focal adhesion location and orientation
- Karin Legerstee
- , Bart Geverts
- & Adriaan B. Houtsmuller
-
Article
| Open Access
Clustering of integrin β cytoplasmic domains triggers nascent adhesion formation and reveals a protozoan origin of the integrin-talin interaction
- Timo Baade
- , Christoph Paone
- & Christof R. Hauck
-
Article
| Open Access
Vinculin Force Sensor Detects Tumor-Osteocyte Interactions
- Fangjia Li
- , Andy Chen
- & Jing Liu
-
Article
| Open Access
Mutant p53 regulates LPA signaling through lysophosphatidic acid phosphatase type 6
- Agnieszka Chryplewicz
- , Samantha M. Tienda
- & Mark A. Eckert
-
Article
| Open Access
The small GTPase RhoG regulates microtubule-mediated focal adhesion disassembly
- Ashtyn Zinn
- , Silvia M. Goicoechea
- & Rafael Garcia-Mata
-
Article
| Open Access
Traction force microscopy with optimized regularization and automated Bayesian parameter selection for comparing cells
- Yunfei Huang
- , Christoph Schell
- & Benedikt Sabass
-
Article
| Open Access
Histamine causes endothelial barrier disruption via Ca2+-mediated RhoA activation and tension at adherens junctions
- Daniela Kugelmann
- , Lukas Thomas Rotkopf
- & Jens Waschke
-
Article
| Open Access
Mechanistic role of transglutaminase-2 in focal adhesions
- Evelyn Png
- , Aihua Hou
- & Louis Tong
-
Article
| Open Access
Vinexin family (SORBS) proteins regulate mechanotransduction in mesenchymal stem cells
- Mito Kuroda
- , Kazumitsu Ueda
- & Noriyuki Kioka
-
Article
| Open Access
Galectin-1 Restricts Vascular Smooth Muscle Cell Motility Via Modulating Adhesion Force and Focal Adhesion Dynamics
- Min-Shao Tsai
- , Ming-Tsai Chiang
- & Lee-Young Chau
-
Article
| Open Access
Live cell imaging reveals focal adhesions mechanoresponses in mammary epithelial cells under sustained equibiaxial stress
- Lorena Sigaut
- , Catalina von Bilderling
- & Lía Isabel Pietrasanta
-
Article
| Open Access
Fabrication of transparent hemispherical 3D nanofibrous scaffolds with radially aligned patterns via a novel electrospinning method
- Jeong In Kim
- , Ju Yeon Kim
- & Chan Hee Park
-
Article
| Open Access
Conformational states during vinculin unlocking differentially regulate focal adhesion properties
- Dror S. Chorev
- , Tova Volberg
- & Benny Geiger
-
Article
| Open Access
Diverse patterns of molecular changes in the mechano-responsiveness of focal adhesions
- Rahuman S. Malik-Sheriff
- , Sarah Imtiaz
- & Eli Zamir
-
Article
| Open Access
Stiffness-dependent motility and proliferation uncoupled by deletion of CD44
- Ziba Razinia
- , Paola Castagnino
- & Richard K. Assoian
-
Article
| Open Access
The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton
- M. Rogg
- , M. Yasuda-Yamahara
- & C. Schell
-
Article
| Open Access
Amniotic membrane promotes focal adhesion remodeling to stimulate cell migration
- Ángel Bernabé-García
- , Sergio Liarte
- & Francisco J. Nicolás
-
Article
| Open Access
Mechanotransduction of matrix stiffness in regulation of focal adhesion size and number: reciprocal regulation of caveolin-1 and β1 integrin
- Yi-Chun Yeh
- , Jin-Ying Ling
- & Ming-Jer Tang
-
Article
| Open Access
Regulation of focal adhesion turnover in SDF-1α-stimulated migration of mesenchymal stem cells in neural differentiation
- Ya’nan Hu
- , Junhou Lu
- & Huanxiang Zhang
-
Article
| Open Access
Src-mediated tyrosine phosphorylation of Protein Kinase D2 at focal adhesions regulates cell adhesion
- Nisha Durand
- , Ligia I. Bastea
- & Peter Storz
-
Article
| Open Access
JMJD3 and NF-κB-dependent activation of Notch1 gene is required for keratinocyte migration during skin wound healing
- Jungtae Na
- , Jee Yoon Shin
- & Bong-Gun Ju
-
Article
| Open Access
High-resolution imaging of a cell-attached nanointerface using a gold-nanoparticle two-dimensional sheet
- Shihomi Masuda
- , Yuhki Yanase
- & Kaoru Tamada
-
Article
| Open Access
Mechanical stability of talin rod controls cell migration and substrate sensing
- Rolle Rahikainen
- , Magdaléna von Essen
- & Vesa P. Hytönen
-
Article
| Open Access
Integrin α2β1 in nonactivated conformation can induce focal adhesion kinase signaling
- Maria Salmela
- , Johanna Jokinen
- & Jyrki Heino
-
Article
| Open Access
Interleukin 22 attenuated angiotensin II induced acute lung injury through inhibiting the apoptosis of pulmonary microvascular endothelial cells
- Zhiyong Wu
- , Zhipeng Hu
- & Bowen Li
-
Article
| Open Access
Endothelial and Astrocytic Support by Human Bone Marrow Stem Cell Grafts into Symptomatic ALS Mice towards Blood-Spinal Cord Barrier Repair
- Svitlana Garbuzova-Davis
- , Crupa Kurien
- & Cesario V. Borlongan
-
Article
| Open Access
Interaction of Src and Alpha-V Integrin Regulates Fibroblast Migration and Modulates Lung Fibrosis in A Preclinical Model of Lung Fibrosis
- Yin-Ying Lu
- , Xue-Ke Zhao
- & Qiang Ding
-
Article
| Open Access
EpCAM Intracellular Domain Promotes Porcine Cell Reprogramming by Upregulation of Pluripotent Gene Expression via Beta-catenin Signaling
- Tong Yu
- , Yangyang Ma
- & Huayan Wang
-
Article
| Open Access
PCTK3/CDK18 regulates cell migration and adhesion by negatively modulating FAK activity
- Shinya Matsuda
- , Kohei Kawamoto
- & Keizo Yuasa
-
Article
| Open Access
Targeted inhibition of Focal Adhesion Kinase Attenuates Cardiac Fibrosis and Preserves Heart Function in Adverse Cardiac Remodeling
- Jie Zhang
- , Guangpu Fan
- & Wei Wang
-
Article
| Open Access
The molecular basis of talin2’s high affinity toward β1-integrin
- Yaxia Yuan
- , Liqing Li
- & Cai Huang
-
Article
| Open Access
Coordinated cell motility is regulated by a combination of LKB1 farnesylation and kinase activity
- S. Wilkinson
- , Y. Hou
- & A. I. Marcus
-
Article
| Open Access
Integrins outside focal adhesions transmit tensions during stable cell adhesion
- Yongliang Wang
- & Xuefeng Wang
-
Article
| Open Access
New structural insight of C-terminal region of Syntenin-1, enhancing the molecular dimerization and inhibitory function related on Syndecan-4 signaling
- Youngsil Choi
- , Ji-Hye Yun
- & Weontae Lee
-
Article
| Open Access
ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions
- Stuart A. Cain
- , Ewa J. Mularczyk
- & Cay M. Kielty
-
Article
| Open Access
Persistence of fan-shaped keratocytes is a matrix-rigidity-dependent mechanism that requires α5β1 integrin engagement
- Maryam Riaz
- , Marie Versaevel
- & Sylvain Gabriele
Targeting cell-derived markers to improve the detection of invisible biological traces for the purpose of genetic-based criminal identification