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| Open AccessAdenoviral vectors encoding CRISPR/Cas9 multiplexes rescue dystrophin synthesis in unselected populations of DMD muscle cells
- Ignazio Maggio
- , Jin Liu
- & Manuel A. F. V. Gonçalves
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| Open AccessDNA annealing by Redβ is insufficient for homologous recombination and the additional requirements involve intra- and inter-molecular interactions
- Sivaraman Subramaniam
- , Axel Erler
- & A. Francis Stewart
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| Open AccessThe pioneering role of PRDM9 indel mutations in tarsier evolution
- Sacha Heerschop
- , Hans Zischler
- & Christine Driller
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| Open AccessAnalysis of gene repair tracts from Cas9/gRNA double-stranded breaks in the human CFTR gene
- Jennifer A. Hollywood
- , Ciaran M. Lee
- & Patrick T. Harrison
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| Open AccessA ‘suicide’ CRISPR-Cas9 system to promote gene deletion and restoration by electroporation in Cryptococcus neoformans
- Yu Wang
- , Dongsheng Wei
- & Xudong Zhu
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| Open AccessPositive Cofactor 4 (PC4) is critical for DNA repair pathway re-routing in DT40 cells
- Randolph B. Caldwell
- , Herbert Braselmann
- & Horst Zitzelsberger
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| Open AccessMolecular cloning, expression and the adjuvant effects of interleukin-8 of channel catfish (Ictalurus Punctatus) against Streptococcus iniae
- Erlong Wang
- , Jun Wang
- & Weimin Lai
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| Open Access“Cre/loxP plus BAC”: a strategy for direct cloning of large DNA fragment and its applications in Photorhabdus luminescens and Agrobacterium tumefaciens
- Shengbiao Hu
- , Zhengqiang Liu
- & Liqiu Xia
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| Open AccessMultigene disruption in undomesticated Bacillus subtilis ATCC 6051a using the CRISPR/Cas9 system
- Kang Zhang
- , Xuguo Duan
- & Jing Wu
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| Open AccessIVA cloning: A single-tube universal cloning system exploiting bacterial In Vivo Assembly
- Javier García-Nafría
- , Jake F. Watson
- & Ingo H. Greger
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| Open AccessThe protein PprI provides protection against radiation injury in human and mouse cells
- Yi Shi
- , Wei Wu
- & Zhanshan Yang
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| Open AccessRAC-tagging: Recombineering And Cas9-assisted targeting for protein tagging and conditional analyses
- Oliver Baker
- , Ashish Gupta
- & A. Francis Stewart
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| Open AccessIdentification and functional analysis of two novel connexin 50 mutations associated with autosome dominant congenital cataracts
- Yinhui Yu
- , Menghan Wu
- & Ke Yao
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| Open AccessIrc3 is a mitochondrial DNA branch migration enzyme
- Ilja Gaidutšik
- , Tiina Sedman
- & Juhan Sedman
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| Open AccessDigital PCR methods improve detection sensitivity and measurement precision of low abundance mtDNA deletions
- Frances R. Belmonte
- , James L. Martin
- & Brett A. Kaufman
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| Open AccessKnots cascade detected by a monotonically decreasing sequence of values
- Xin Liu
- & Renzo L. Ricca
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| Open AccessThe RecQ DNA helicase Rqh1 constrains Exonuclease 1-dependent recombination at stalled replication forks
- Fekret Osman
- , Jong Sook Ahn
- & Matthew C. Whitby
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| Open AccessGenetic engineering and heterologous expression of the disorazol biosynthetic gene cluster via Red/ET recombineering
- Qiang Tu
- , Jennifer Herrmann
- & Rolf Müller
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| Open AccessLight-inducible genetic engineering and control of non-homologous end-joining in industrial eukaryotic microorganisms: LML 3.0 and OFN 1.0
- Lei Zhang
- , Xihua Zhao
- & Dongzhi Wei
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| Open AccessThree DUF1996 Proteins Localize in Vacuoles and Function in Fungal Responses to Multiple Stresses and Metal Ions
- Sen-Miao Tong
- , Ying Chen
- & Ming-Guang Feng
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| Open AccessKnockin of Cre Gene at Ins2 Locus Reveals No Cre Activity in Mouse Hypothalamic Neurons
- Ling Li
- , Lin Gao
- & Weiping J. Zhang
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| Open AccessConstruction of a subunit-fusion nitrile hydratase and discovery of an innovative metal ion transfer pattern
- Yuanyuan Xia
- , Wenjing Cui
- & Zhemin Zhou
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| Open AccessA human monoclonal antibody against HPV16 recognizes an immunodominant and neutralizing epitope partially overlapping with that of H16.V5
- Lin Xia
- , Yangfei Xian
- & Ningshao Xia
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| Open AccessREPLACR-mutagenesis, a one-step method for site-directed mutagenesis by recombineering
- Ashutosh Trehan
- , Michał Kiełbus
- & Adolfo Rivero-Müller
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| Open AccessBiochemical Characterization of Nonamer Binding Domain of RAG1 Reveals its Thymine Preference with Respect to Length and Position
- Deepthi Raveendran
- & Sathees C. Raghavan
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| Open AccessTATA boxes in gene transcription and poly (A) tails in mRNA stability: New perspective on the effects of berberine
- Zhi-Yi Yuan
- , Xi Lu
- & Li-Jun Du
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| Open AccessCRISPR/Cas9-mediated knockout of factors in non-homologous end joining pathway enhances gene targeting in silkworm cells
- Li Zhu
- , Hiroaki Mon
- & Takahiro Kusakabe
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| Open AccessSeven gene deletions in seven days: Fast generation of Escherichia coli strains tolerant to acetate and osmotic stress
- Sheila I. Jensen
- , Rebecca M. Lennen
- & Alex T. Nielsen
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| Open AccessFragmented mitochondrial genomes in two suborders of parasitic lice of eutherian mammals (Anoplura and Rhynchophthirina, Insecta)
- Renfu Shao
- , Stephen C Barker
- & Yuan Su
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| Open AccessEpitopes in α8β1 and other RGD-binding integrins delineate classes of integrin-blocking antibodies and major binding loops in α subunits
- Norihisa Nishimichi
- , Nagako Kawashima
- & Yasuyuki Yokosaki
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| Open AccessRapGene: a fast and accurate strategy for synthetic gene assembly in Escherichia coli
- Massimiliano Zampini
- , Pauline Rees Stevens
- & Finbarr Hayes
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| Open AccessConservation of writhe helicity under anti-parallel reconnection
- Christian E. Laing
- , Renzo L. Ricca
- & De Witt L. Sumners
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| Open AccessAn efficient strategy for producing a stable, replaceable, highly efficient transgene expression system in silkworm, Bombyx mori
- Dingpei Long
- , Weijian Lu
- & Aichun Zhao
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| Open AccessSomatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model
- Miwa Tanaka
- , Shuichi Yamaguchi
- & Takuro Nakamura
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| Open AccessUnglycosylated recombinant human glutathione peroxidase 3 mutant from Escherichia coli is active as a monomer
- Jian Song
- , Yang Yu
- & Hongwei Song
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| Open AccessGenetic evidence suggests that Spata22 is required for the maintenance of Rad51 foci in mammalian meiosis
- Satoshi Ishishita
- , Yoichi Matsuda
- & Kazuhiro Kitada
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| Open AccessNap1 stimulates homologous recombination by RAD51 and RAD54 in higher-ordered chromatin containing histone H1
- Shinichi Machida
- , Motoki Takaku
- & Hitoshi Kurumizaka
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| Open AccessCombinatorial gene editing in mammalian cells using ssODNs and TALENs
- Bryan Strouse
- , Pawel Bialk
- & Eric B. Kmiec
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| Open AccessProducing aglycons of ginsenosides in bakers' yeast
- Zhubo Dai
- , Beibei Wang
- & Xueli Zhang
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| Open AccessCharacterization of GM events by insert knowledge adapted re-sequencing approaches
- Litao Yang
- , Congmao Wang
- & Dabing Zhang
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| Open AccessThe proteasome factor Bag101 binds to Rad22 and suppresses homologous recombination
- Yuichiro Saito
- , Jun Takeda
- & Toshiaki Isobe
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| Open AccessNovel Nanosomes for Gene Delivery to Plasmodium falciparum-infected Red Blood Cells
- Anusha M. Gopalakrishnan
- , Anup K. Kundu
- & Nirbhay Kumar
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| Open AccessExplicit hypoxia targeting with tumor suppression by creating an “obligate” anaerobic Salmonella Typhimurium strain
- Bin Yu
- , Mei Yang
- & Jian-Dong Huang
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| Open AccessTandem assembly of the epothilone biosynthetic gene cluster by in vitro site-specific recombination
- Lin Zhang
- , Guoping Zhao
- & Xiaoming Ding