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| Open AccessIn-vitro and in-vivo assessment of nirmatrelvir penetration into CSF, central nervous system cells, tissues, and peripheral blood mononuclear cells
- Sean N. Avedissian
- , Johid R. Malik
- & Courtney V. Fletcher
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| Open AccessApomorphine is a potent inhibitor of ferroptosis independent of dopaminergic receptors
- Akihiko Miyauchi
- , Chika Watanabe
- & Hitoshi Osaka
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| Open AccessForensic investigation of falsified antimalarials using isotope ratio mass spectrometry: a pilot investigation
- Paul N. Newton
- , Lesley A. Chesson
- & Thure E. Cerling
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| Open AccessPsychedelics and sexual functioning: a mixed-methods study
- Tommaso Barba
- , Hannes Kettner
- & Bruna Giribaldi
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| Open AccessExploring the impact of naltrexone on the THBS1/eNOS/NO pathway in osteoporotic bile duct-ligated rats
- Seyed Reza Hosseini-Fard
- , Shahroo Etemad-Moghadam
- & Abolfazl Golestani
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| Open AccessEfficacy and safety of 5-hydroxytryptamine-3 (5-HT3) receptor antagonists in augmentation with selective serotonin reuptake inhibitors (SSRIs) in the treatment of moderate to severe obsessive–compulsive disorder: a systematic review and meta-analysis of randomized clinical trials
- Negin Eissazade
- , Hesam Mosavari
- & Mohammadreza Shalbafan
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| Open AccessAbuse liability of two electronic nicotine delivery systems compared with combustible cigarettes and nicotine gum from an open-label randomized crossover study
- Chris Campbell
- , Tao Jin
- & Sarah Baxter
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| Open AccessReproducibility in pharmacometrics applied in a phase III trial of BCG-vaccination for COVID-19
- Rob C. van Wijk
- , Laurynas Mockeliunas
- & Ulrika S. H. Simonsson
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| Open AccessPhysiologically-based pharmacokinetic modeling for optimal dosage prediction of olaparib when co-administered with CYP3A4 modulators and in patients with hepatic/renal impairment
- Dongmei Gao
- , Guopeng Wang
- & Jiawei Ren
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| Open AccessCo-use of MDMA with psilocybin/LSD may buffer against challenging experiences and enhance positive experiences
- Richard J. Zeifman
- , Hannes Kettner
- & Robin L. Carhart-Harris
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| Open AccessExploring the association between selective serotonin reuptake inhibitors and rhabdomyolysis risk based on the FDA pharmacovigilance database
- Yan Wang
- , Yajing Lin
- & Dongbo Jiang
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| Open AccessPregnancy outcomes after vaginal probiotic supplementation before frozen embryo transfer: a randomized controlled study
- Isarin Thanaboonyawat
- , Sootthinan Pothisan
- & Pitak Laokirkkiat
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| Open AccessEvaluation and comparison of pharmacokinetic profiles and safety of two extended-release buprenorphine formulations in common marmosets (Callithrix jacchus)
- Niora J. Fabian
- , Anthony J. Mannion
- & Jennifer L. Haupt
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| Open AccessThe effect of intravenous granisetron on prophylactic ephedrine for preventing hypotension after general anaesthesia induction in elderly patients: a randomized controlled trial
- Youfa Zhou
- , Cencen Wang
- & Gang Chen
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| Open AccessMeasuring the diversity gap of cannabis clinical trial participants compared to people who report using cannabis
- Heather Barkholtz
- & Maia Bates
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| Open AccessSitagliptin ameliorates busulfan-induced pulmonary and testicular injury in rats through antioxidant, anti-inflammatory, antifibrotic, and antiapoptotic effects
- Eman A. Ali
- , Sara G. Tayel
- & Mona A. Abbas
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| Open AccessEvaluation of rosuvastatin-induced QT prolongation risk using real-world data, in vitro cardiomyocyte studies, and mortality assessment
- Yeryung Koo
- , Sung-Ae Hyun
- & Dukyong Yoon
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| Open AccessIn vitro PCR verification that lysozyme inhibits nucleic acid replication and transcription
- Lu Liu
- , Xu Jia
- & Qian Zheng
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| Open AccessExploring the components and mechanisms of Shen-qi-wang-mo granule in the treatment of retinal vein occlusion by UPLC-Triple TOF MS/MS and network pharmacology
- Yi Zhao
- , Cui Ma
- & Zhenghua Wu
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| Open AccessApplication of a physiologically based pharmacokinetic model in predicting captopril disposition in children with chronic kidney disease
- Sundus Khalid
- , Muhammad Fawad Rasool
- & Faleh Alqahtani
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| Open AccessDevelopmental changes in the extent of drug binding to rat plasma proteins
- Fiona Qiu
- , Katarzyna M. Dziegielewska
- & Norman R. Saunders
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| Open AccessA randomized pharmacological fMRI trial investigating d-cycloserine and brain plasticity mechanisms in learned pain responses
- Mia A. Thomaidou
- , Joseph S. Blythe
- & Andrea W. M. Evers
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| Open AccessRemimazolam besylate for the sedation of postoperative patients undergoing invasive mechanical ventilation in the ICU: a prospective dose‒response study
- Xiaoyan Chen
- , Jiancheng Zhang
- & Haiyan Huang
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| Open AccessImpact of intravenous dexmedetomidine on gastrointestinal function recovery after laparoscopic hysteromyomectomy: a randomized clinical trial
- Yu Wu
- , Zenghua Cai
- & Ni An
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| Open AccessEffect of interleukin-1 blockade with anakinra on leukocyte count in patients with ST-segment elevation acute myocardial infarction
- Marco Giuseppe Del Buono
- , Juan Ignacio Damonte
- & Antonio Abbate
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| Open AccessThe effectiveness of split tablet dosing versus alternate-day dosing of warfarin: a randomized control trial
- Chanyapat Kaewsaengeak
- , Usanee Pienputtarapong
- & Teerapong Tocharoenchok
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| Open AccessAssociation of metformin use with Alzheimer’s disease in patients with newly diagnosed type 2 diabetes: a population-based nested case–control study
- Junghee Ha
- , Dong-Woo Choi
- & Eosu Kim
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| Open AccessExcessive unbound cefazolin concentrations in critically ill patients receiving veno-arterial extracorporeal membrane oxygenation (vaECMO): an observational study
- Hendrik Booke
- , Otto R. Frey
- & Elisabeth H. Adam
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| Open AccessPharmacological and clinical evaluation of deferasirox formulations for treatment tailoring
- Andrea Piolatto
- , Paola Berchialla
- & Filomena Longo
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| Open AccessA simple method to measure sulfonation in man using paracetamol as probe drug
- Natália Marto
- , Judit Morello
- & Sofia A. Pereira
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| Open AccessA novel method for the storage and transport of biological samples of therapeutic proteins prior to the detection of analytes using ELISA
- Lei Wang
- , Lixiong Liu
- & Zeneng Cheng
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| Open AccessDevelopment and evaluation of physiologically based pharmacokinetic drug-disease models for predicting captopril pharmacokinetics in chronic diseases
- Muhammad F. Rasool
- , Shazia Ali
- & Faleh Alqahtani
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| Open AccessPolypill eligibility and equivalent intake in a Swiss population-based study
- Julien Castioni
- , Nazanin Abolhassani
- & Pedro Marques-Vidal
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| Open AccessConcomitant drugs associated with increased mortality for MDMA users reported in a drug safety surveillance database
- Isaac V. Cohen
- , Tigran Makunts
- & Kelan Thomas
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| Open AccessEnteric reabsorption processes and their impact on drug pharmacokinetics
- Manuel Ibarra
- , Iñaki F. Trocóniz
- & Pietro Fagiolino
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| Open AccessA network meta-analysis of the dose–response effects of lurasidone on acute schizophrenia
- Manit Srisurapanont
- , Sirijit Suttajit
- & Narong Maneeton
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| Open AccessThe effectiveness of Bacopa monnieri (Linn.) Wettst. as a nootropic, neuroprotective, or antidepressant supplement: analysis of the available clinical data
- James M. Brimson
- , Sirikalaya Brimson
- & Tewin Tencomnao
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| Open AccessEarly impact of donor CYP3A5 genotype and Graft-to-Recipient Weight Ratio on tacrolimus pharmacokinetics in pediatric liver transplant patients
- Michele Pinon
- , Amedeo De Nicolò
- & Pier Luigi Calvo
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| Open AccessDrugs with anti-inflammatory effects to improve outcome of traumatic brain injury: a meta-analysis
- Marieke Begemann
- , Mikela Leon
- & Iris Sommer
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| Open AccessTreatment optimization of beta-blockers in chronic heart failure therapy
- Yirga Legesse Niriayo
- , Solomon Weldegebreal Asgedom
- & Kidu Gidey
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| Open AccessCombinations of common SNPs of the transporter gene ABCB1 influence apparent bioavailability, but not renal elimination of oral digoxin
- Chih-hsuan Hsin
- , Marc S. Stoffel
- & Max Taubert
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| Open AccessOptimizing Exogenous Surfactant as a Pulmonary Delivery Vehicle for Chicken Cathelicidin-2
- Brandon Baer
- , Edwin J. A. Veldhuizen
- & Ruud Veldhuizen
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| Open AccessFisetin induces apoptosis in uterine leiomyomas through multiple pathways
- Jin-Woo Lee
- , Hyuck Jai Choi
- & Kyung Sook Kim
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| Open AccessProstaglandin F2α agonist-induced suppression of 3T3-L1 cell adipogenesis affects spatial formation of extra-cellular matrix
- Yosuke Ida
- , Fumihito Hikage
- & Hiroshi Ohguro
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| Open AccessExploring the role of the Ser9Gly (rs6280) Dopamine D3 receptor polymorphism in nicotine reinforcement and cue-elicited craving
- Chidera C. Chukwueke
- , William J. Kowalczyk
- & Bernard Le Foll
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| Open AccessThe Effects of Sildenafil and/or Nitroglycerin on Random-pattern Skin Flaps After Nicotine Application in Rats
- Mohamed A. Ellabban
- , Islam Omar Abdel Fattah
- & Suhail Masadeh
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| Open AccessELISA assay employing epitope-specific monoclonal antibodies to quantify circulating HER2 with potential application in monitoring cancer patients undergoing therapy with trastuzumab
- Valentina Agnolon
- , Anna Contato
- & Aline S. C. Fabricio
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| Open AccessBile acid bio-nanoencapsulation improved drug targeted-delivery and pharmacological effects via cellular flux: 6-months diabetes preclinical study
- Armin Mooranian
- , Susbin Raj Wagle
- & Hani Al-Salami
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| Open AccessInfluence of OATP1B1 and BCRP polymorphisms on the pharmacokinetics and pharmacodynamics of rosuvastatin in elderly and young Korean subjects
- Yun Kim
- , Seonghae Yoon
- & Jae-Yong Chung