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| Open AccessEpigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia
- Zachary C. Rosenthal
- , Daniel M. Fass
- & Stephen J. Haggarty
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| Open AccessIdentification and structural characterization of small molecule inhibitors of PINK1
- Shafqat Rasool
- , Tara Shomali
- & Jean-François Trempe
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| Open AccessDiscovery of a cystathionine γ-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5′-phosphate (PLP) via Schiff base formation
- Honami Echizen
- , Kenjiro Hanaoka
- & Yasuteru Urano
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| Open AccessModulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis
- Frances M. Bashore
- , Ariana B. Marquez
- & Alison D. Axtman
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| Open AccessThe cytotoxic activity of carfilzomib together with nelfinavir is superior to the bortezomib/nelfinavir combination in non-small cell lung carcinoma
- Lenka Besse
- , Marianne Kraus
- & Ignazio Tarantino
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| Open AccessUtility of fatty acid profile and in vitro immune cell activation for chemical and biological standardization of Arthrospira/Limnospira
- Jungmoo Huh
- , Jin Zhang
- & Nirmal D. Pugh
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| Open AccessDevelopment of Safirinium dyes for new applications: fluorescent staining of bacteria, human kidney cells, and the horny layer of the epidermis
- Joanna Fedorowicz
- , Dagmara Bazar
- & Jarosław Sączewski
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| Open AccessPiezo1 activation using Yoda1 inhibits macropinocytosis in A431 human epidermoid carcinoma cells
- Masashi Kuriyama
- , Hisaaki Hirose
- & Shiroh Futaki
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| Open AccessFörster resonance energy transfer biosensors for fluorescence and time-gated luminescence analysis of rac1 activity
- Ha Pham
- , Mona Hoseini Soflaee
- & Lawrence W. Miller
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| Open AccessNigratine as dual inhibitor of necroptosis and ferroptosis regulated cell death
- Claire Delehouzé
- , Arnaud Comte
- & Stéphane Bach
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| Open AccessVolatile organic compound profiling to explore primary graft dysfunction after lung transplantation
- Pierre-Hugues Stefanuto
- , Rosalba Romano
- & Jane E. Hill
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| Open AccessExperimental evolution supports the potential of neonicotinoid-pyrethroid combination for managing insecticide resistance in malaria vectors
- Marius Gonse Zoh
- , Jean-Marc Bonneville
- & Jean-Philippe David
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| Open AccessMicro-Chamber/Thermal Extractor (µ-CTE) as a new sampling system for VOCs emitted by feces
- Ileana Andreea Ratiu
- , Radik Mametov
- & Bogusław Buszewski
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| Open AccessSynthetic design of farnesyl-electrostatic peptides for development of a protein kinase A membrane translocation switch
- Allen K. Kim
- , Helen D. Wu
- & Takanari Inoue
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| Open AccessMetabolic labeling with an alkyne probe reveals similarities and differences in the prenylomes of several brain-derived cell lines and primary cells
- Kiall F. Suazo
- , Angela Jeong
- & Mark D. Distefano
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| Open AccessTerroir and vintage discrimination of Malbec wines based on phenolic composition across multiple sites in Mendoza, Argentina
- Roy Urvieta
- , Gregory Jones
- & Ariel Fontana
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| Open AccessDiscovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery
- Lyra Chang
- , James Campbell
- & Damian W. Young
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| Open AccessFluorescent ligands for dopamine D2/D3 receptors
- Anni Allikalt
- , Nirupam Purkayastha
- & Dorothee Weikert
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| Open AccessExploring food contents in scientific literature with FoodMine
- Forrest Hooton
- , Giulia Menichetti
- & Albert-László Barabási
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| Open AccessVisualizing the dynamics of exported bacterial proteins with the chemogenetic fluorescent reporter FAST
- Yankel Chekli
- , Caroline Peron-Cane
- & Christophe Beloin
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| Open AccessBardoxolone conjugation enables targeted protein degradation of BRD4
- Bingqi Tong
- , Mai Luo
- & Daniel K. Nomura
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| Open AccessHybrid Harris hawks optimization with cuckoo search for drug design and discovery in chemoinformatics
- Essam H. Houssein
- , Mosa E. Hosney
- & M. Hassaballah
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| Open AccessGeneration of interconnected vesicles in a liposomal cell model
- Baharan Ali Doosti
- , Daniel Fjällborg
- & Tatsiana Lobovkina
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| Open AccessEpigenetics meets GPCR: inhibition of histone H3 methyltransferase (G9a) and histamine H3 receptor for Prader–Willi Syndrome
- David Reiner
- , Ludwig Seifert
- & Holger Stark
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| Open AccessEffect of lysine side chain length on histone lysine acetyltransferase catalysis
- Giordano Proietti
- , Yali Wang
- & Jasmin Mecinović
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| Open AccessN,N-Dimethylaminopyrene as a fluorescent affinity mass tag for ligand-binding mode analysis
- Atsushi Arai
- , Rei Watanabe
- & Masaki Kita
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| Open AccessInterplay between Cellular Uptake, Intracellular Localization and the Cell Death Mechanism in Triphenylamine-Mediated Photoinduced Cell Death
- Rahima Chennoufi
- , Ngoc-Duong Trinh
- & Eric Deprez
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| Open AccessHoechst-tagged Fluorescein Diacetate for the Fluorescence Imaging-based Assessment of Stomatal Dynamics in Arabidopsis thaliana
- Yousuke Takaoka
- , Saki Miyagawa
- & Minoru Ueda
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Article
| Open AccessTracing multi-isotopically labelled CdSe/ZnS quantum dots in biological media
- N. Izyan Supiandi
- , G. Charron
- & Y. Sivry
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| Open AccessSynthetic analogues of 2-oxo acids discriminate metabolic contribution of the 2-oxoglutarate and 2-oxoadipate dehydrogenases in mammalian cells and tissues
- Artem V. Artiukhov
- , Aneta Grabarska
- & Victoria I. Bunik
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| Open AccessOne-Pot Radiosynthesis and Biological Evaluation of a Caspase-3 Selective 5-[123,125I]iodo-1,2,3-triazole derived Isatin SPECT Tracer
- Matthias Glaser
- , Vineeth Rajkumar
- & Erik Årstad
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| Open AccessFunctional annotation of serine hydrolases in the asexual erythrocytic stage of Plasmodium falciparum
- Rubayet Elahi
- , W. Keith Ray
- & Michael Klemba
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| Open AccessChemical activation of divergent protein tyrosine phosphatase domains with cyanine-based biarsenicals
- Bailey A. Plaman
- , Wai Cheung Chan
- & Anthony C. Bishop
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| Open AccessIn vitro inhibition of human red blood cell acetylcholinesterase (AChE) by temephos-oxidized products
- Francisco Alberto Verdín-Betancourt
- , Mario Figueroa
- & Adolfo Sierra-Santoyo
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| Open AccessPotent modulation of the CepR quorum sensing receptor and virulence in a Burkholderia cepacia complex member using non-native lactone ligands
- Betty L. Slinger
- , Jacqueline J. Deay
- & Helen E. Blackwell
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| Open AccessRapid and efficient high-performance liquid chromatography analysis of N-nitrosodimethylamine impurity in valsartan drug substance and its products
- Sayaka Masada
- , Genichiro Tsuji
- & Haruhiro Okuda
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| Open AccessProbing the effect(s) of the microwaves’ electromagnetic fields in enzymatic reactions
- Satoshi Horikoshi
- , Kota Nakamura
- & Nick Serpone
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| Open AccessTargeting the neuronal calcium sensor DREAM with small-molecules for Huntington’s disease treatment
- Alejandro Lopez-Hurtado
- , Diego A. Peraza
- & Marta Gutierrez-Rodriguez
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| Open AccessCell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines
- Sanjay G. Patel
- , Edward J. Sayers
- & Yu-Hsuan Tsai
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| Open AccessGreen barley mitigates cytotoxicity in human lymphocytes undergoing aggressive oxidative stress, via activation of both the Lyn/PI3K/Akt and MAPK/ERK pathways
- Blanca E. Ruiz-Medina
- , Dennise Lerma
- & Elisa Robles-Escajeda
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| Open AccessAnalysis of α-dicarbonyl compounds and volatiles formed in Maillard reaction model systems
- Jiyoon Cha
- , Trishna Debnath
- & Kwang-Geun Lee
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| Open AccessA MALDI-TOF-based Method for Studying the Transport of BBB Shuttles—Enhancing Sensitivity and Versatility of Cell-Based In Vitro Transport Models
- Pol Arranz-Gibert
- , Bernat Guixer
- & Meritxell Teixidó
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| Open AccessLeaf Disc Assays for Rapid Measurement of Antioxidant Activity
- Deepak M. Kasote
- , Guddadarangavvanahally K. Jayaprakasha
- & Bhimanagouda S. Patil
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| Open AccessA Novel Ruthenium-based Molecular Sensor to Detect Endothelial Nitric Oxide
- Achini K. Vidanapathirana
- , Benjamin J. Pullen
- & Peter J. Psaltis
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| Open AccessStructure-efficiency relationship of photoinduced electron transfer-triggered nitric oxide releasers
- Naoya Ieda
- , Yumina Oka
- & Hidehiko Nakagawa
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| Open AccessA continuous fluorescence assay for simple quantification of bile salt hydrolase activity in the gut microbiome
- Kristoffer R. Brandvold
- , Jacqueline M. Weaver
- & Aaron T. Wright
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| Open AccessRapid detection of metastatic lymph nodes of colorectal cancer with a gamma-glutamyl transpeptidase-activatable fluorescence probe
- Hidemasa Kubo
- , Kenjiro Hanaoka
- & Yasuteru Urano
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| Open AccessProbing of G-Quadruplex Structures via Ligand-Sensitized Photochemical Reactions in BrU-Substituted DNA
- Abhijit Saha
- , Sophie Bombard
- & Marie-Paule Teulade-Fichou
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| Open AccessLive Cell Imaging of Bioorthogonally Labelled Proteins Generated With a Single Pyrrolysine tRNA Gene
- Noa Aloush
- , Tomer Schvartz
- & Eyal Arbely