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| Open AccessRandom Matrix Analysis for Gene Interaction Networks in Cancer Cells
- Ayumi Kikkawa
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| Open AccessMicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium
- Bence Ágg
- , Tamás Baranyai
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| Open AccessA gene co-expression network model identifies yield-related vicinity networks in Jatropha curcas shoot system
- Nisha Govender
- , Siju Senan
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| Open AccessModel of the adaptive immune response system against HCV infection reveals potential immunomodulatory agents for combination therapy
- Ayesha Obaid
- , Anam Naz
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| Open AccessNon-coding RNAs in Various Stages of Liver Disease Leading to Hepatocellular Carcinoma: Differential Expression of miRNAs, piRNAs, lncRNAs, circRNAs, and sno/mt-RNAs
- Srinivas V. Koduru
- , Ashley N. Leberfinger
- & Dino J. Ravnic
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| Open AccessA logic-based method to build signaling networks and propose experimental plans
- Adrien Rougny
- , Pauline Gloaguen
- & Christine Froidevaux
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| Open AccessAurora kinase A (AURKA) interaction with Wnt and Ras-MAPK signalling pathways in colorectal cancer
- Annika Jacobsen
- , Linda J. W. Bosch
- & K. Anton Feenstra
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Article
| Open AccessFunctional and structural characterization of osteocytic MLO-Y4 cell proteins encoded by genes differentially expressed in response to mechanical signals in vitro
- Fanchi Meng
- , Graeme F. Murray
- & Henry J. Donahue
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| Open AccessIntegrated analysis of microRNA and mRNA expression profiles in rats with selenium deficiency and identification of associated miRNA-mRNA network
- Yanjing Feng
- , Yunjie Xing
- & Dengfeng Gao
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Article
| Open AccessIdentification of the functional pathways altered by placental cell exposure to high glucose: lessons from the transcript and metabolite interactome
- C. H. Hulme
- , A. Stevens
- & J. E. Myers
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| Open AccessTopological estimation of signal flow in complex signaling networks
- Daewon Lee
- & Kwang-Hyun Cho
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Article
| Open AccessPhenotype-driven identification of epithelial signalling clusters
- Elsa Marques
- , Tomi Peltola
- & Juha Klefström
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Article
| Open AccessAnalyzing the genes related to nicotine addiction or schizophrenia via a pathway and network based approach
- Ying Hu
- , Zhonghai Fang
- & Ju Wang
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Article
| Open AccessMolecular mechanisms of detection and discrimination of dynamic signals
- G. Antunes
- , A. C. Roque
- & F. M. Simoes-de-Souza
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Article
| Open AccessComparative phosphoproteomic analysis reveals signaling networks regulating monopolar and bipolar cytokinesis
- Özge Karayel
- , Erdem Şanal
- & Nurhan Özlü
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| Open AccessPancreatic gene expression during recovery after pancreatitis reveals unique transcriptome profiles
- Kristy Boggs
- , Ting Wang
- & Sohail Z. Husain
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Article
| Open AccessQuantitative assessment of cell fate decision between autophagy and apoptosis
- Bing Liu
- , Zoltán N. Oltvai
- & Ivet Bahar
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Article
| Open AccessModulation of Immune Signaling and Metabolism Highlights Host and Fungal Transcriptional Responses in Mouse Models of Invasive Pulmonary Aspergillosis
- Shiv D. Kale
- , Tariq Ayubi
- & Josep Bassaganya-Riera
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Article
| Open AccessIdentification of genes expressed in a mesenchymal subset regulating prostate organogenesis using tissue and single cell transcriptomics
- Nadia Boufaied
- , Claire Nash
- & Axel A. Thomson
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Article
| Open AccessDiscovery of High-Affinity PDGF-VEGFR Interactions: Redefining RTK Dynamics
- Spencer B. Mamer
- , Si Chen
- & P. I. Imoukhuede
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Article
| Open AccessInformation processing in the NF-κB pathway
- Karolina Tudelska
- , Joanna Markiewicz
- & Tomasz Lipniacki
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Article
| Open AccessPredicted molecular targets and pathways for germacrone, curdione, and furanodiene in the treatment of breast cancer using a bioinformatics approach
- Qi Kong
- , Yong Ma
- & Xiuping Chen
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Article
| Open AccessPredicting Causal Relationships from Biological Data: Applying Automated Causal Discovery on Mass Cytometry Data of Human Immune Cells
- Sofia Triantafillou
- , Vincenzo Lagani
- & Ioannis Tsamardinos
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Article
| Open AccessEffect of Transforming Growth Factor-β upon Taenia solium and Taenia crassiceps Cysticerci
- Laura Adalid-Peralta
- , Gabriela Rosas
- & Gladis Fragoso
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Article
| Open AccessStructural insights into the Middle East respiratory syndrome coronavirus 4a protein and its dsRNA binding mechanism
- Maria Batool
- , Masaud Shah
- & Sangdun Choi
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Article
| Open AccessComplete sequence-based pathway analysis by differential on-chip DNA and RNA extraction from a single cell
- D. van Strijp
- , R. C. M. Vulders
- & P. J. van der Zaag
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Article
| Open AccessCODA: Integrating multi-level context-oriented directed associations for analysis of drug effects
- Hasun Yu
- , Jinmyung Jung
- & Doheon Lee
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Article
| Open AccessA single amino acid substitution confers B-cell clonogenic activity to the HIV-1 matrix protein p17
- Cinzia Giagulli
- , Pasqualina D’Ursi
- & Arnaldo Caruso
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| Open AccessBenchmarking selected computational gene network growing tools in context of virus-host interactions
- Biruhalem Taye
- , Candida Vaz
- & Sebastian Maurer-Stroh
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Article
| Open AccessReconstruction of pathway modification induced by nicotinamide using multi-omic network analyses in triple negative breast cancer
- Ji Young Kim
- , Hyebin Lee
- & Han Suk Ryu
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Article
| Open AccessComparative morphology and transcriptome analysis reveals distinct functions of the primary and secondary laticifer cells in the rubber tree
- Deguan Tan
- , Xiaowen Hu
- & Jiaming Zhang
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Article
| Open AccessCharacterization of developmental defects in the forebrain resulting from hyperactivated mTOR signaling by integrative analysis of transcriptomic and proteomic data
- Jiheon Shin
- , Minhyung Kim
- & Jaesang Kim
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Article
| Open AccessDifferential processing of small RNAs during endoplasmic reticulum stress
- Mikhail V. Mesitov
- , Ruslan A. Soldatov
- & Aleksey A. Moskovtsev
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Article
| Open AccessSTAT3 and NF-κB are Simultaneously Suppressed in Dendritic Cells in Lung Cancer
- Rui Li
- , Fang Fang
- & Weihua Xiao
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| Open AccessEarly spatiotemporal-specific changes in intermediate signals are predictive of cytotoxic sensitivity to TNFα and co-treatments
- Lit-Hsin Loo
- , Nicola Michelle Bougen-Zhukov
- & Wei-Ling Cecilia Tan
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Article
| Open AccessStructure-Activity Relationship in TLR4 Mutations: Atomistic Molecular Dynamics Simulations and Residue Interaction Network Analysis
- Muhammad Ayaz Anwar
- & Sangdun Choi
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Article
| Open AccessData-Driven Discovery of Extravasation Pathway in Circulating Tumor Cells
- S. Yadavalli
- , S. Jayaram
- & P. Kumar
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| Open AccessA Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity
- Gregory Riddick
- , Svetlana Kotliarova
- & Howard A. Fine
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| Open AccessContext-independent essential regulatory interactions for apoptosis and hypertrophy in the cardiac signaling network
- Jun Hyuk Kang
- , Ho-Sung Lee
- & Kwang-Hyun Cho
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| Open AccessMechanistic interplay between ceramide and insulin resistance
- Federico Reali
- , Melissa J. Morine
- & Corrado Priami
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Article
| Open AccessPredicting Drug Combination Index and Simulating the Network-Regulation Dynamics by Mathematical Modeling of Drug-Targeted EGFR-ERK Signaling Pathway
- Lu Huang
- , Yuyang Jiang
- & Yuzong Chen
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| Open AccessThe metastasis suppressor RARRES3 as an endogenous inhibitor of the immunoproteasome expression in breast cancer cells
- Alison M. Anderson
- , Murugan Kalimutho
- & Mark A. Ragan
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Article
| Open AccessRelaxation oscillations and hierarchy of feedbacks in MAPK signaling
- Marek Kochańczyk
- , Paweł Kocieniewski
- & Tomasz Lipniacki
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| Open AccessMulti-label ℓ2-regularized logistic regression for predicting activation/inhibition relationships in human protein-protein interaction networks
- Suyu Mei
- & Kun Zhang
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Article
| Open AccessKnowledge-guided fuzzy logic modeling to infer cellular signaling networks from proteomic data
- Hui Liu
- , Fan Zhang
- & Jie Zheng
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Article
| Open AccessEnhanced release of primary signals may render intercellular signalling ineffective due to spatial aspects
- Pavel Kundrát
- & Werner Friedland
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Article
| Open AccessA self-enhanced transport mechanism through long noncoding RNAs for X chromosome inactivation
- Chunhe Li
- , Tian Hong
- & Qing Nie
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Article
| Open AccessComputational discovery of Epstein-Barr virus targeted human genes and signalling pathways
- Suyu Mei
- & Kun Zhang
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| Open AccessSystems view of adipogenesis via novel omics-driven and tissue-specific activity scoring of network functional modules
- Isar Nassiri
- , Rosario Lombardo
- & Corrado Priami