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| Open AccessKlotho inhibits IGF1R/PI3K/AKT signalling pathway and protects the heart from oxidative stress during ischemia/reperfusion injury
- Agnieszka Olejnik
- , Anna Radajewska
- & Iwona Bil-Lula
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| Open AccessPPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation
- Chiaki Inoue
- , Kojiro Mukai
- & Tomohiko Taguchi
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| Open AccessRNF2 regulates Wnt/ß-catenin signaling via TCF7L1 destabilization
- Youngmu Koo
- , Wonhee Han
- & Jin-Kwan Han
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| Open AccessIL-4 and IL-13 induce equivalent expression of traditional M2 markers and modulation of reactive oxygen species in human macrophages
- Tara E. Scott
- , Caitlin V. Lewis
- & Barbara K. Kemp-Harper
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| Open AccessTranscriptome analysis reveals the impact of NETs activation on airway epithelial cell EMT and inflammation in bronchiolitis obliterans
- Zhongji Wu
- , Xiaowen Chen
- & Dehui Chen
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| Open AccessStarvation induces changes in abundance and small RNA cargo of extracellular vesicles released from Plasmodium falciparum infected red blood cells
- Leonie Vetter
- , Amanj Bajalan
- & Ulf Ribacke
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| Open AccessProtein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice
- Karel F. A. Van Damme
- , Pieter Hertens
- & Geert van Loo
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| Open AccessMuscarinic receptor agonist-induced βPix binding to β-catenin promotes colon neoplasia
- Kunrong Cheng
- , Ahmed Chahdi
- & Jean-Pierre Raufman
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| Open AccessA synthetic coolant (WS-23) in disposable electronic cigarettes impairs cytoskeletal function in EpiAirway microtissues exposed at the air liquid interface
- Man Wong
- , Teresa Martinez
- & Prue Talbot
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| Open AccessAllosteric modulation of the fish taste receptor type 1 (T1R) family by the extracellular chloride ion
- Ryusei Goda
- , Soichi Watanabe
- & Takumi Misaka
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| Open AccessVascular smooth muscle cells enhance immune/vascular interplay in a 3-cell model of vascular inflammation
- Jolanta Wiejak
- , Fiona A. Murphy
- & Stephen J. Yarwood
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| Open AccessComputational evidence for multi-layer crosstalk between the cadherin-11 and PDGFR pathways
- Zeynep Karagöz
- , Fiona R. Passanha
- & Aurélie Carlier
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| Open AccessEffect of extracellular vesicles derived from induced pluripotent stem cells on mesangial cells underwent a model of fibrosis in vitro
- Bruno Aristides dos Santos Bronel
- , Edgar Maquigussa
- & Antônio da Silva Novaes
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| Open AccessCoixendide efficacy in combination with temozolomide in glioblastoma and transcriptome analysis of the mechanism
- Zhenran Zhao
- , Lei Zhang
- & Peng Jin
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| Open AccessOxidative stress induces mitochondrial iron overload and ferroptotic cell death
- Yi Chen
- , Xiaoyun Guo
- & Qinghang Liu
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| Open AccessRegulation of follicular activation signaling pathways by in vitro inhibition of YAP/TAZ activity in mouse ovaries
- Melody Devos
- , Joana Dias Nunes
- & Isabelle Demeestere
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| Open AccessLeft ventricular hypertrophy and metabolic resetting in the Notch3-deficient adult mouse heart
- Francesca Del Gaudio
- , Dongli Liu
- & Urban Lendahl
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| Open AccessDifferential intracellular management of fatty acids impacts on metabolic stress-stimulated glucose uptake in cardiomyocytes
- Ettore Vanni
- , Karina Lindner
- & Christophe Montessuit
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| Open AccessInhibitory effect of Sanguisorba hakusanensis Makino ethanol extract on atopic dermatitis-like responses in NC/Nga mice and human keratinocytes
- Hyun-Kyung Song
- , Sun Haeng Park
- & Taesoo Kim
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| Open AccessInterlukin-4 weakens resistance to stress injury and megakaryocytic differentiation of hematopoietic stem cells by inhibiting Psmd13 expression
- Ai Gao
- , Shuhui Xu
- & Yuemin Gong
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| Open AccessEvidence of natural selection in the mitochondrial-derived peptides humanin and SHLP6
- James M. Gruschus
- , Daniel L. Morris
- & Nico Tjandra
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| Open AccessCardamonin protects against iron overload induced arthritis by attenuating ROS production and NLRP3 inflammasome activation via the SIRT1/p38MAPK signaling pathway
- Shaocong Li
- , Qi He
- & Jianfa Chen
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| Open AccessOne-carbon metabolizing enzyme ALDH1L1 influences mitochondrial metabolism through 5-aminoimidazole-4-carboxamide ribonucleotide accumulation and serine depletion, contributing to tumor suppression
- Masato Sasaki
- , Kazuo Yamamoto
- & Nobuyuki Shibata
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| Open AccessActivation of cAMP (EPAC2) signaling pathway promotes hepatocyte attachment
- Grace Aprilia Helena
- , Teruhiko Watanabe
- & Shoen Kume
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| Open AccessComparing the signaling and transcriptome profiling landscapes of human iPSC-derived and primary rat neonatal cardiomyocytes
- Kyla Bourque
- , Jace Jones-Tabah
- & Terence E. Hébert
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| Open AccessNewt A1 cell-derived extracellular vesicles promote mammalian nerve growth
- Ryan C. Middleton
- , Ke Liao
- & Eduardo Marbán
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| Open AccessThe human acetylcholinesterase C-terminal T30 peptide activates neuronal growth through alpha 7 nicotinic acetylcholine receptors and the mTOR pathway
- Alexandru Graur
- , Patricia Sinclair
- & Nadine Kabbani
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| Open AccessProteomic analysis of the effect of hemin in breast cancer
- G. P. Coló
- , K. Schweitzer
- & M. M. Facchinetti
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| Open AccessPasteurization of human milk affects the miRNA cargo of EVs decreasing its immunomodulatory activity
- Monica F. Torrez Lamberti
- , Leslie A. Parker
- & Graciela L. Lorca
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| Open AccessFatty acid fingerprints in bronchoalveolar lavage fluid and its extracellular vesicles reflect equine asthma severity
- Nina Höglund
- , Petteri Nieminen
- & Anna Mykkänen
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| Open AccessSimultaneous reduction of all ORMDL proteins decreases the threshold of mast cell activation
- Livia Demkova
- , Viktor Bugajev
- & Ivana Halova
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| Open AccessMechanical-induced bone remodeling does not depend on Piezo1 in dentoalveolar hard tissue
- Cita Nottmeier
- , Josef Lavicky
- & Julian Petersen
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| Open AccessOpposite modulation of functional recovery following contusive spinal cord injury in mice with oligodendrocyte-selective deletions of Atf4 and Chop/Ddit3
- Yonglin Gao
- , George Z. Wei
- & Michal Hetman
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| Open AccessMembrane estrogen receptor α signaling modulates the sensitivity to estradiol treatment in a dose- and tissue- dependent manner
- Yiwen Jiang
- , Karin Horkeby
- & Marie K. Lagerquist
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| Open AccessHuman soluble CD39 displays substrate inhibition in a substrate-specific manner
- Venkat M. K. Vadlamani
- , Kavinda K. J. Gunasinghe
- & Matthew T. Harper
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| Open AccessMicrofibril-associated protein 5 and the regulation of skin scar formation
- Chen Han
- , Trevor R. Leonardo
- & Luisa A. DiPietro
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| Open AccessTranscriptional analysis reveals that the intracellular lipid accumulation impairs gene expression profiles involved in insulin response-associated cardiac functionality
- Virginia Actis Dato
- , María C. Paz
- & Danilo G. Ceschin
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| Open AccessStreptozotocin induces renal proximal tubular injury through p53 signaling activation
- Kunihiro Nakai
- , Minato Umehara
- & Tetsuro Kusaba
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| Open AccessNanoscale thermal control of a single living cell enabled by diamond heater-thermometer
- Alexey M. Romshin
- , Vadim Zeeb
- & Igor I. Vlasov
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| Open AccessDeletion of endothelial leptin receptors in mice promotes diet-induced obesity
- Rajinikanth Gogiraju
- , Claudius Witzler
- & Katrin Schäfer
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| Open AccessPARP2 poly(ADP-ribosyl)ates nuclear factor erythroid 2-related factor 2 (NRF2) affecting NRF2 subcellular localization
- Laura Jankó
- , Emese Tóth
- & Péter Bai
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| Open AccessMultimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation
- Kyle Ford
- , Brenton P. Munson
- & Trey Ideker
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| Open AccessFluorescence resonance energy transfer (FRET) spatiotemporal mapping of atypical P38 reveals an endosomal and cytosolic spatial bias
- Jeremy C. Burton
- , Jennifer Okalova
- & Neil J. Grimsey
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| Open AccessHigh concentrations of soluble endoglin can inhibit BMP9 signaling in non-endothelial cells
- Clara Andersson-Rusch
- , Bin Liu
- & Wei Li
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| Open AccessAlpha-linolenic acid modulates systemic and adipose tissue-specific insulin sensitivity, inflammation, and the endocannabinoid system in dairy cows
- Gitit Kra
- , Jayasimha Rayalu Daddam
- & Maya Zachut
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| Open AccessPhosphate induces inflammation and exacerbates injury from cigarette smoke in the bronchial epithelium
- Seth Bollenbecker
- , Kylie Heitman
- & Stefanie Krick
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| Open AccessHeat shock protein A2 is a novel extracellular vesicle-associated protein
- Damian Robert Sojka
- , Agata Abramowicz
- & Dorota Scieglinska
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| Open AccessExtracellular vesicles are dynamic regulators of maternal glucose homeostasis during pregnancy
- Hannah C. Zierden
- , Ruth Marx-Rattner
- & Tracy L. Bale
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| Open AccessInhibition of NHE1 transport activity and gene transcription in DRG neurons in oxaliplatin-induced painful peripheral neurotoxicity
- Marianna Dionisi
- , Beatrice Riva
- & Guido Cavaletti