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Modeling mutation-specific arrhythmogenic phenotypes in isogenic human iPSC-derived cardiac tissues
- Thomas L. Maurissen
- , Masahide Kawatou
- & Knut Woltjen
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| Open Access
CRISPR/Cas9-mediated knock-in of BRCA1/2 mutations restores response to olaparib in pancreatic cancer cell lines
- Andréa Witz
- , Julie Dardare
- & Alexandre Harlé
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| Open Access
Generation of CRISPR-Cas9-mediated knockin mutant models in mice and MEFs for studies of polymorphism in clock genes
- Kwangjun Lee
- & Choogon Lee
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| Open Access
Rapid clonal identification of biallelic CRISPR/Cas9 knock-ins using SNEAK PEEC
- Sameer Singh
- , Anoosha Banerjee
- & Sebastian Klinge
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| Open Access
Efficient simultaneous double DNA knock-in in murine embryonic stem cells by CRISPR/Cas9 ribonucleoprotein-mediated circular plasmid targeting for generating gene-manipulated mice
- Manabu Ozawa
- , Jumpei Taguchi
- & Masahito Ikawa
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| Open Access
Suppressing gain-of-function proteins via CRISPR/Cas9 system in SCA1 cells
- Mariangela Pappadà
- , Ottavia Bonuccelli
- & Peggy Marconi
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| Open Access
CRISPR/Cas9-based genome-wide screening of Dictyostelium
- Takanori Ogasawara
- , Jun Watanabe
- & Tetsuya Muramoto
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| Open Access
Experimental strategies to achieve efficient targeted knock-in via tandem paired nicking
- Md. Lutfur Rahman
- , Toshinori Hyodo
- & Hiroyuki Konishi
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| Open Access
Efficient biallelic knock-in in mouse embryonic stem cells by in vivo-linearization of donor and transient inhibition of DNA polymerase θ/DNA-PK
- Daisuke Arai
- & Yoichi Nakao
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| Open Access
Manipulation of the Tyrosinase gene permits improved CRISPR/Cas editing and neural imaging in cichlid fish
- Cheng-Yu Li
- , Joshua R. Steighner
- & Scott A. Juntti
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| Open Access
HtrA4 is up-regulated during trophoblast syncytialization and BeWo cells fail to syncytialize without HtrA4
- Mary Mansilla
- , Yao Wang
- & Guiying Nie
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| Open Access
Genome-wide CRISPR/Cas9 screening in human iPS derived cardiomyocytes uncovers novel mediators of doxorubicin cardiotoxicity
- Valerie Sapp
- , Aitor Aguirre
- & Mohit Jain
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| Open Access
A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells
- Benjamin Lindner
- , Eva Martin
- & Michael Schuler
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| Open Access
CRISPR-mediated mutations in the ABC transporter gene ABCA2 confer pink bollworm resistance to Bt toxin Cry2Ab
- Jeffrey A. Fabrick
- , Dannialle M. LeRoy
- & Bruce E. Tabashnik
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| Open Access
Efficient genome editing of an extreme thermophile, Thermus thermophilus, using a thermostable Cas9 variant
- Bjorn Thor Adalsteinsson
- , Thordis Kristjansdottir
- & Gudmundur Oli Hreggvidsson
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| Open Access
Knockout of zebrafish desmin genes does not cause skeletal muscle degeneration but alters calcium flux
- Gülsüm Kayman Kürekçi
- , Ecem Kural Mangit
- & Pervin R. Dincer
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| Open Access
CRISPR-based transcriptional activation tool for silent genes in filamentous fungi
- László Mózsik
- , Mirthe Hoekzema
- & Arnold J. M. Driessen
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| Open Access
Improving CRISPR/Cas9 mutagenesis efficiency by delaying the early development of zebrafish embryos
- M. Terzioglu
- , A. Saralahti
- & J.-O. Andressoo
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| Open Access
Genome editing with the donor plasmid equipped with synthetic crRNA-target sequence
- Riki Ishibashi
- , Kota Abe
- & Fumiko Toyoshima
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| Open Access
Rapid repair of human disease-specific single-nucleotide variants by One-SHOT genome editing
- Yuji Yokouchi
- , Shinichi Suzuki
- & Takumi Era
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| Open Access
Physiological impact and comparison of mutant screening methods in piwil2 KO founder Nile tilapia produced by CRISPR/Cas9 system
- Ye Hwa Jin
- , Baoshan Liao
- & Andrew Davie
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| Open Access
Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish
- Rakesh Kumar Banote
- , Jasmine Chebli
- & Henrik Zetterberg
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| Open Access
Production of genetically engineered mice with higher efficiency, lower mosaicism, and multiplexing capability using maternally expressed Cas9
- Takayuki Sakurai
- , Akiko Kamiyoshi
- & Takayuki Shindo
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| Open Access
Efficient production and transmission of CRISPR/Cas9-mediated mutant alleles at the IG-DMR via generation of mosaic mice using a modified 2CC method
- Satoshi Hara
- , Miho Terao
- & Shuji Takada
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| Open Access
Reporter lines based on the gexp02 promoter enable early quantification of sexual conversion rates in the malaria parasite Plasmodium falciparum
- Harvie P. Portugaliza
- , Oriol Llorà-Batlle
- & Alfred Cortés
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| Open Access
Efficient generation of Knock-in/Knock-out marmoset embryo via CRISPR/Cas9 gene editing
- Wakako Kumita
- , Kenya Sato
- & Erika Sasaki
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| Open Access
CRISPR/Cas9-mediated ablation of elovl2 in Atlantic salmon (Salmo salar L.) inhibits elongation of polyunsaturated fatty acids and induces Srebp-1 and target genes
- Alex K. Datsomor
- , Nikola Zic
- & Per Winge
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| Open Access
The mineralocorticoid receptor is essential for stress axis regulation in zebrafish larvae
- Erin Faught
- & Mathilakath M. Vijayan
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| Open Access
Effects of CRISPR/Cas9 dosage on TICAM1 and RBL gene mutation rate, embryonic development, hatchability and fry survival in channel catfish
- Ahmed Elaswad
- , Karim Khalil
- & Rex Dunham
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| Open Access
i-GONAD (improved genome-editing via oviductal nucleic acids delivery), a convenient in vivo tool to produce genome-edited rats
- Shuji Takabayashi
- , Takuya Aoshima
- & Masahiro Sato
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| Open Access
CRISPR/Cas9 mediated targeting of multiple genes in Dictyostelium
- Ryoya Sekine
- , Takefumi Kawata
- & Tetsuya Muramoto
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| Open Access
‘Cold shock’ increases the frequency of homology directed repair gene editing in induced pluripotent stem cells
- Q. Guo
- , G. Mintier
- & John N. Feder
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| Open Access
Efficient inhibition of African swine fever virus replication by CRISPR/Cas9 targeting of the viral p30 gene (CP204L)
- Alexandra Hübner
- , Bjoern Petersen
- & Walter Fuchs
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| Open Access
A surrogate reporter system for multiplexable evaluation of CRISPR/Cas9 in targeted mutagenesis
- Hongmin Zhang
- , Yuexin Zhou
- & Wensheng Wei
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| Open Access
Site-specific randomization of the endogenous genome by a regulatable CRISPR-Cas9 piggyBac system in human cells
- Kentaro Ishida
- , Huaigeng Xu
- & Akitsu Hotta
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| Open Access
Combined shRNA over CRISPR/cas9 as a methodology to detect off-target effects and a potential compensatory mechanism
- Liat Peretz
- , Elazar Besser
- & Oded Behar
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| Open Access
Development of a versatile and conventional technique for gene disruption in filamentous fungi based on CRISPR-Cas9 technology
- Yan-Mei Zheng
- , Fu-Long Lin
- & Dan Hu
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| Open Access
Alteration of sheep coat color pattern by disruption of ASIP gene via CRISPR Cas9
- Xuemei Zhang
- , Wenrong Li
- & Mingjun Liu
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| Open Access
Modeling Dominant and Recessive Forms of Retinitis Pigmentosa by Editing Three Rhodopsin-Encoding Genes in Xenopus Laevis Using Crispr/Cas9
- Joanna M. Feehan
- , Colette N. Chiu
- & Orson L. Moritz
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| Open Access
CRISPR/Cas9-mediated mutation of tyrosinase (Tyr) 3′ UTR induce graying in rabbit
- Yuning Song
- , Yuxin Xu
- & Zhanjun Li
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| Open Access
Generation of heritable germline mutations in the jewel wasp Nasonia vitripennis using CRISPR/Cas9
- Ming Li
- , Lauren Yun Cook Au
- & Omar S. Akbari
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| Open Access
A novel tool for monitoring endogenous alpha-synuclein transcription by NanoLuciferase tag insertion at the 3′end using CRISPR-Cas9 genome editing technique
- Sambuddha Basu
- , Levi Adams
- & Yoon-Seong Kim
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| Open Access
CRISPR/Cas9-mediated efficient genome editing via blastospore-based transformation in entomopathogenic fungus Beauveria bassiana
- Jingjing Chen
- , Yiling Lai
- & Sibao Wang
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| Open Access
A Convenient Cas9-based Conditional Knockout Strategy for Simultaneously Targeting Multiple Genes in Mouse
- Jiang Chen
- , Yinan Du
- & Yun S. Shi
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| Open Access
Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease
- Kelsey E. Jarrett
- , Ciaran M. Lee
- & William R. Lagor
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| Open Access
Illegitimate translation causes unexpected gene expression from on-target out-of-frame alleles created by CRISPR-Cas9
- Shigeru Makino
- , Ryutaro Fukumura
- & Yoichi Gondo
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| Open Access
Multiplex CRISPR/Cas9-based genome engineering enhanced by Drosha-mediated sgRNA-shRNA structure
- Qiang Yan
- , Kun Xu
- & Zhiying Zhang
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| Open Access
Internal epitope tagging informed by relative lack of sequence conservation
- Leonard Burg
- , Karen Zhang
- & Darius Balciunas
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| Open Access
Functional visualization and disruption of targeted genes using CRISPR/Cas9-mediated eGFP reporter integration in zebrafish
- Satoshi Ota
- , Kiyohito Taimatsu
- & Atsuo Kawahara
APEX2-based proximity proteomic analysis identifies candidate interactors for Plasmodium falciparum knob-associated histidine-rich protein in infected erythrocytes