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| Open AccessA novel T cell-redirecting anti-GPRC5D × CD3 bispecific antibody with potent antitumor activity in multiple myeloma preclinical models
- Urara Tomita
- , Yoko Ishimoto
- & Toshinori Agatsuma
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| Open AccessA pan-influenza monoclonal antibody neutralizes H5 strains and prophylactically protects through intranasal administration
- Anna L. Beukenhorst
- , Jacopo Frallicciardi
- & Jaap Goudsmit
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| Open AccessComprehensive modeling of cell culture profile using Raman spectroscopy and machine learning
- Hiroki Tanemura
- , Ryunosuke Kitamura
- & Koichi Nonaka
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| Open AccessHigh-throughput analysis system of interaction kinetics for data-driven antibody design
- Ryo Matsunaga
- , Kan Ujiie
- & Kouhei Tsumoto
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| Open AccessDiagnostic utility of N-terminal TMPP labels for unambiguous identification of clipped sites in therapeutic proteins
- Harsha P. Gunawardena
- , Meth M. Jayatilake
- & Hirsh Nanda
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| Open AccessInsights into next generation sequencing guided antibody selection strategies
- M. Frank Erasmus
- , Fortunato Ferrara
- & Andrew R. M. Bradbury
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| Open AccessPreclinical immunological characterization of rademikibart (CBP-201), a next-generation human monoclonal antibody targeting IL-4Rα, for the treatment of Th2 inflammatory diseases
- Limin Zhang
- , Ying Ding
- & Xin Yang
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| Open AccessCross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy
- Christoffer V. Sørensen
- , Line Ledsgaard
- & Andreas H. Laustsen
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| Open AccessFc-competent multispecific PDL-1/TIGIT/LAG-3 antibodies potentiate superior anti-tumor T cell response
- Riyao Yang
- , Su Huang
- & Yue Liu
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| Open AccessTozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction
- Elizabeth England
- , D. Gareth Rees
- & E. Suzanne Cohen
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| Open AccessCharacterization of human anti-EpCAM antibodies for developing an antibody–drug conjugate
- Hiroyuki Satofuka
- , Yayan Wang
- & Yasuhiro Kazuki
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| Open AccessDevelopment of an inhibiting antibody against equine interleukin 5 to treat insect bite hypersensitivity of horses
- Nora Langreder
- , Dorina Schäckermann
- & Michael Hust
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| Open AccessAntibody-dependent cellular cytotoxicity-null effector developed using mammalian and plant GlycoDelete platform
- Cho Eun Kang
- , Seungeun Lee
- & Woo Taek Kim
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| Open AccessA novel anti-TNF-α drug ozoralizumab rapidly distributes to inflamed joint tissues in a mouse model of collagen induced arthritis
- Shohei Oyama
- , Kosuke Ebina
- & Ken Nakata
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| Open AccessFirst-in-class trispecific VHH-Fc based antibody with potent prophylactic and therapeutic efficacy against SARS-CoV-2 and variants
- Allison Titong
- , Sachith Gallolu Kankanamalage
- & Yue Liu
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| Open AccessTwo novel human anti-CD25 antibodies with antitumor activity inversely related to their affinity and in vitro activity
- Deyong Song
- , Xiu Liu
- & Changlin Dou
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| Open AccessPeptide barcoding for one-pot evaluation of sequence–function relationships of nanobodies
- Yusei Matsuzaki
- , Wataru Aoki
- & Mitsuyoshi Ueda
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| Open AccessNanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients
- Jonathan Marable
- , Damien Ruiz
- & Maninder Sandey
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| Open AccessProduction of IgG1-based bispecific antibody without extra cysteine residue via intein-mediated protein trans-splicing
- Hiroki Akiba
- , Tomoko Ise
- & Kouhei Tsumoto
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| Open AccessPreclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel disease
- Kevin J. Roberts
- , Marion F. Cubitt
- & J. Scott Crowe
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| Open AccessGeneration of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning
- Lauric Haber
- , Kara Olson
- & Eric Smith
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| Open AccessAn engineered tetra-valent antibody fully activates the Tie2 receptor with comparable potency to its natural ligand angiopoietin-1
- Yukari Koya
- , Hiromi Nara
- & Masazumi Kamohara
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| Open AccessA scDb-based trivalent bispecific antibody for T-cell-mediated killing of HER3-expressing cancer cells
- Nadine Aschmoneit
- , Sophia Steinlein
- & Roland E. Kontermann
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| Open AccessMultiplexed engineering glycosyltransferase genes in CHO cells via targeted integration for producing antibodies with diverse complex-type N-glycans
- Ngan T. B. Nguyen
- , Jianer Lin
- & Yuansheng Yang
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| Open AccessFreeze–thaw characterization process to minimize aggregation and enable drug product manufacturing of protein based therapeutics
- Keethkumar Jain
- , Nazila Salamat-Miller
- & Katherine Taylor
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| Open AccessA bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo expansion of CD8 and NK cells
- Katherine E. Harris
- , Kyle J. Lorentsen
- & Nathan D. Trinklein
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| Open AccessDevelopment and characterization of two equine formulations towards SARS-CoV-2 proteins for the potential treatment of COVID-19
- Guillermo León
- , María Herrera
- & Alberto Alape
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| Open AccessEffect of disease modifying anti-rheumatic drugs on major cardiovascular events: a meta-analysis of randomized controlled trials
- Shivshankar Thanigaimani
- , James Phie
- & Jonathan Golledge
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| Open AccessSafety of switching between rituximab biosimilars in onco-hematology
- Silvana A. M. Urru
- , Stefania Spila Alegiani
- & Annalisa Campomori
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| Open AccessNon-specific interactions of antibody-oligonucleotide conjugates with living cells
- Victor Lehot
- , Isabelle Kuhn
- & Alain Wagner
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| Open AccessAnti-EGFR antibody 528 binds to domain III of EGFR at a site shifted from the cetuximab epitope
- Koki Makabe
- , Takeshi Yokoyama
- & Izumi Kumagai
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| Open AccessNovel myostatin-specific antibody enhances muscle strength in muscle disease models
- Hiroyasu Muramatsu
- , Taichi Kuramochi
- & Junichi Nezu
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| Open AccessWashing with alkaline solutions in protein A purification improves physicochemical properties of monoclonal antibodies
- Yuichi Imura
- , Toshiaki Tagawa
- & Hideo Miki
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| Open AccessImprovement of Certolizumab Fab′ properties by PASylation technology
- Somayeh Mazaheri
- , Yeganeh Talebkhan
- & Fatemeh Torkashvand
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| Open AccessDevelopment of humanized tri-specific nanobodies with potent neutralization for SARS-CoV-2
- Jianbo Dong
- , Betty Huang
- & Yue Liu
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| Open AccessThe influence of proline isomerization on potency and stability of anti-HIV antibody 10E8
- Miklos Guttman
- , Neal N. Padte
- & Kelly K. Lee
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| Open AccessAntibody-protein binding and conformational changes: identifying allosteric signalling pathways to engineer a better effector response
- Mohammed M. Al Qaraghuli
- , Karina Kubiak-Ossowska
- & Paul A. Mulheran
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| Open AccessA novel therapeutic antibody screening method using bacterial high-content imaging reveals functional antibody binding phenotypes of Escherichia coli ST131
- Mailis Maes
- , Zoe A. Dyson
- & Josefin Bartholdson Scott
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| Open AccessIn Pursuit of Stability Enhancement of a Prostate Cancer Targeting Antibody Derived from a Transgenic Animal Platform
- Sathya Venkataramani
- , Robin Ernst
- & Rajkumar Ganesan
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| Open AccessHigh-Throughput Generation of Bipod (Fab × scFv) Bispecific Antibodies Exploits Differential Chain Expression and Affinity Capture
- Thomas C. Nesspor
- , Kyle Kinealy
- & Adam Zwolak
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| Open AccessPlant-based production of highly potent anti-HIV antibodies with engineered posttranslational modifications
- Advaita Acarya Singh
- , Ofentse Pooe
- & Rachel Chikwamba
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| Open AccessAntibody transcytosis across brain endothelial-like cells occurs nonspecifically and independent of FcRn
- John S. Ruano-Salguero
- & Kelvin H. Lee
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| Open AccessDevelopment of the clinical candidate PBD-C06, a humanized pGlu3-Aβ-specific antibody against Alzheimer’s disease with reduced complement activation
- Thore Hettmann
- , Stephen D. Gillies
- & Inge Lues
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| Open AccessGolden Gate assembly with a bi-directional promoter (GBid): A simple, scalable method for phage display Fab library creation
- Karuppiah Chockalingam
- , Zeyu Peng
- & Zhilei Chen
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| Open AccessNanodisc technology facilitates identification of monoclonal antibodies targeting multi-pass membrane proteins
- Bernd Gardill
- , Jerry Huang
- & Christy A. Thomson
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| Open AccessHuman antibodies neutralizing diphtheria toxin in vitro and in vivo
- Esther Veronika Wenzel
- , Margarita Bosnak
- & Michael Hust
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| Open AccessCharacterization of IgG1 Fc Deamidation at Asparagine 325 and Its Impact on Antibody-dependent Cell-mediated Cytotoxicity and FcγRIIIa Binding
- Xiaojun Lu
- , Lee Ann Machiesky
- & Jihong Wang
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| Open AccessBiochemical and biophysical characterization of purified native CD20 alone and in complex with rituximab and obinutuzumab
- Morgane Agez
- , Elodie Desuzinges Mandon
- & Anass Jawhari
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| Open AccessUse of syngeneic cells expressing membrane-bound GM-CSF as an adjuvant to induce antibodies against native multi-pass transmembrane protein
- Chien-Chiao Huang
- , Kai-Wen Cheng
- & Tian-Lu Cheng