Amyotrophic lateral sclerosis articles within Scientific Reports

Featured

• Article
  26 April 2024 | Open Access

  Online speech synthesis using a chronically implanted brain–computer interface in an individual with ALS

  • Miguel Angrick
  • , Shiyu Luo
  •  & Nathan E. Crone

• Article
  11 March 2024 | Open Access

  Evidence for disrupted copper availability in human spinal cord supports Cu^II(atsm) as a treatment option for sporadic cases of ALS

  • James B. W. Hilton
  • , Kai Kysenius
  •  & Peter J. Crouch

• Article
  20 December 2023 | Open Access

  Reconstitution of C9orf72 GGGGCC repeat-associated non-AUG translation with purified human translation factors

  • Hayato Ito
  • , Kodai Machida
  •  & Hideki Taguchi

• Article
  06 December 2023 | Open Access

  AI-assisted quantification of hypothalamic atrophy in amyotrophic lateral sclerosis by convolutional neural network-based automatic segmentation

  • Ina Vernikouskaya
  • , Hans-Peter Müller
  •  & Volker Rasche

• Article
  24 November 2023 | Open Access

  Accurate personalized survival prediction for amyotrophic lateral sclerosis patients

  • Li-Hao Kuan
  • , Pedram Parnianpour
  •  & Russell Greiner

• Article
  10 November 2023 | Open Access

  Cystatin C based estimation of chronic kidney disease and amyotrophic lateral sclerosis in the ALS registry Swabia: associated risk and prognostic value

  • Gabriele Nagel
  • , Deborah Kurz
  •  & Dietrich Rothenbacher

• Article
  23 August 2023 | Open Access

  miRNA profiling as a complementary diagnostic tool for amyotrophic lateral sclerosis

  • Jack Cheng
  • , Wen-Kuang Ho
  •  & Wei-Yong Lin

• Article
  26 July 2023 | Open Access

  Prospective study to evaluate quality of life in amyotrophic lateral sclerosis

  • Candela Caballero-Eraso
  • , Carlos Carrera-Cueva
  •  & Luis Jara-Palomares

• Article
  25 July 2023 | Open Access

  Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients

  • Volkan Yazar
  • , Julia K. Kühlwein
  •  & Karin M. Danzer

• Article
  21 April 2023 | Open Access

  Cortical glia in SOD1(G93A) mice are subtly affected by ALS-like pathology

  • Tereza Filipi
  • , Zuzana Matusova
  •  & Miroslava Anderova

• Article
  12 April 2023 | Open Access

  Mutant and curli-producing E. coli enhance the disease phenotype in a hSOD1-G93A mouse model of ALS

  • Zimple Kurlawala
  • , Joseph D. McMillan
  •  & Robert P. Friedland

• Article
  09 March 2023 | Open Access

  Motor unit number index (MUNIX) loss of 50% occurs in half the time of 50% functional loss according to the D50 disease progression model of ALS

  • Theresa Ebersbach
  • , Annekathrin Roediger
  •  & Julian Grosskreutz

• Article
  23 February 2023 | Open Access

  NOTCH2NLC GGC repeats are not expanded in Italian amyotrophic lateral sclerosis patients

  • Arianna Manini
  • , Delia Gagliardi
  •  & Dario Ronchi

• Article
  09 December 2022 | Open Access

  Molecular basis of C9orf72 poly-PR interference with the β-karyopherin family of nuclear transport receptors

  • Hamidreza Jafarinia
  • , Erik Van der Giessen
  •  & Patrick R. Onck

• Article
  11 October 2022 | Open Access

  A novel assessment of fine-motor function reveals early hindlimb and detectable forelimb deficits in an experimental model of ALS

  • C. Sahara Khademullah
  •  & Yves De Koninck

• Article
  03 October 2022 | Open Access

  Optimized multi-echo gradient-echo magnetic resonance imaging for gray and white matter segmentation in the lumbosacral cord at 3 T

  • Silvan Büeler
  • , Marios C. Yiannakas
  •  & Gergely David

• Article
  26 September 2022 | Open Access

  Motor unit number index (MUNIX) in the D50 disease progression model reflects disease accumulation independently of disease aggressiveness in ALS

  • Theresa Ebersbach
  • , Annekathrin Roediger
  •  & Julian Grosskreutz

• Article
  02 September 2022 | Open Access

  Importance of the Q/N-rich segment for protein stability of endogenous mouse TDP-43

  • Toshiya Sato
  • , Kanako Oda
  •  & Minesuke Yokoyama

• Article
  30 August 2022 | Open Access

  A new method for estimating under-recruitment of a patient registry: a case study with the Ohio Registry of Amyotrophic Lateral Sclerosis

  • Meifang Li
  • , Xun Shi
  •  & Walter G. Bradley

• Article
  22 July 2022 | Open Access

  Amyotrophic lateral sclerosis and cerebellum

  • Renata Kabiljo
  • , Alfredo Iacoangeli
  •  & Ivana Rosenzweig

• Article
  05 May 2022 | Open Access

  Hyperexcitability in young iPSC-derived C9ORF72 mutant motor neurons is associated with increased intracellular calcium release

  • Sarah Burley
  • , Dayne A. Beccano-Kelly
  •  & Richard Wade-Martins

• Article
  05 April 2022 | Open Access

  Dual-gRNA approach with limited off-target effect corrects C9ORF72 repeat expansion in vivo

  • Xuejiao Piao
  • , Dawei Meng
  •  & Yichang Jia

• Article
  01 April 2022 | Open Access

  Body fat compartment determination by encoder–decoder convolutional neural network: application to amyotrophic lateral sclerosis

  • Ina Vernikouskaya
  • , Hans-Peter Müller
  •  & Volker Rasche

• Article
  17 March 2022 | Open Access

  Argonaute 2 is lost from neuromuscular junctions affected with amyotrophic lateral sclerosis in SOD1^G93A mice

  • Dillon Shapiro
  • , Ryan Massopust
  •  & Gregorio Valdez

• Article
  11 March 2022 | Open Access

  Mitochondrial dysregulation occurs early in ALS motor cortex with TDP-43 pathology and suggests maintaining NAD⁺ balance as a therapeutic strategy

  • Mukesh Gautam
  • , Aksu Gunay
  •  & P. Hande Ozdinler

• Article
  07 January 2022 | Open Access

  SOD1 mutations associated with amyotrophic lateral sclerosis analysis of variant severity

  • Mariusz Berdyński
  • , Przemysław Miszta
  •  & Magdalena Kuźma-Kozakiewicz

• Article
  12 November 2021 | Open Access

  A selectable all-in-one CRISPR prime editing piggyBac transposon allows for highly efficient gene editing in human cell lines

  • Reto Eggenschwiler
  • , Thomas Gschwendtberger
  •  & Tobias Cantz

• Article
  11 November 2021 | Open Access

  Neurofilaments can differentiate ALS subgroups and ALS from common diagnostic mimics

  • Arvin Behzadi
  • , Fani Pujol-Calderón
  •  & Peter Munch Andersen

• Article
  29 September 2021 | Open Access

  CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1^G93A mice with a C57BL/6 background

  • Jeremy S. Lum
  • , Mikayla L. Brown
  •  & Justin J. Yerbury

• Article
  23 September 2021 | Open Access

  Neuronal mitochondrial dysfunction in sporadic amyotrophic lateral sclerosis is developmentally regulated

  • Tanisha Singh
  • , Yuanyuan Jiao
  •  & Diane L. Carlisle

• Article
  09 September 2021 | Open Access

  Prognostic prediction by hypermetabolism varies depending on the nutritional status in early amyotrophic lateral sclerosis

  • Ryutaro Nakamura
  • , Mika Kurihara
  •  & Makoto Urushitani

• Article
  02 September 2021 | Open Access

  Protein disulphide isomerase (PDI) is protective against amyotrophic lateral sclerosis (ALS)-related mutant Fused in Sarcoma (FUS) in in vitro models

  • S. Parakh
  • , E. R. Perri
  •  & J. D. Atkin

• Article
  12 August 2021 | Open Access

  Clearance of peripheral nerve misfolded mutant protein by infiltrated macrophages correlates with motor neuron disease progression

  • Wataru Shiraishi
  • , Ryo Yamasaki
  •  & Jun-ichi Kira

• Article
  30 June 2021 | Open Access

  Lipidomics study of plasma from patients suggest that ALS and PLS are part of a continuum of motor neuron disorders

  • Estela Area-Gomez
  • , D. Larrea
  •  & H. Mitsumoto

• Article
  10 June 2021 | Open Access

  NMJ-Analyser identifies subtle early changes in mouse models of neuromuscular disease

  • Alan Mejia Maza
  • , Seth Jarvis
  •  & Carole H. Sudre

• Article
  08 June 2021 | Open Access

  FGF23, a novel muscle biomarker detected in the early stages of ALS

  • Ying Si
  • , Mohamed Kazamel
  •  & Peter H. King

• Article
  07 June 2021 | Open Access

  Residential exposure to electromagnetic fields and risk of amyotrophic lateral sclerosis: a dose–response meta-analysis

  • Tommaso Filippini
  • , Elizabeth E. Hatch
  •  & Marco Vinceti

• Article
  26 May 2021 | Open Access

  Oxaloacetate treatment preserves motor function in SOD1^G93A mice and normalizes select neuroinflammation-related parameters in the spinal cord

  • Sudheer K. Tungtur
  • , Heather M. Wilkins
  •  & Hiroshi Nishimune

• Article
  17 May 2021 | Open Access

  Characterization of the human TARDBP gene promoter

  • Marco Baralle
  •  & Maurizio Romano

• Article
  26 January 2021 | Open Access

  Motor cortical excitability predicts cognitive phenotypes in amyotrophic lateral sclerosis

  • Smriti Agarwal
  • , Elizabeth Highton-Williamson
  •  & Matthew C. Kiernan

• Article
  30 November 2020 | Open Access

  IL-10 based immunomodulation initiated at birth extends lifespan in a familial mouse model of amyotrophic lateral sclerosis

  • Michael R. Strickland
  • , Kristen R. Ibanez
  •  & Paramita Chakrabarty

• Article
  26 November 2020 | Open Access

  Premature termination codons in SOD1 causing Amyotrophic Lateral Sclerosis are predicted to escape the nonsense-mediated mRNA decay

  • Claire Guissart
  • , Kevin Mouzat
  •  & Serge Lumbroso

• Article
  05 November 2020 | Open Access

  Female sex mitigates motor and behavioural phenotypes in TDP-43^Q331K knock-in mice

  • Jodie Watkins
  • , Anshua Ghosh
  •  & Jemeen Sreedharan

• Article
  07 October 2020 | Open Access

  Wnt antagonist FRZB is a muscle biomarker of denervation atrophy in amyotrophic lateral sclerosis

  • Thaddaeus Kwan
  • , Mohamed Kazamel
  •  & Peter H. King

• Article
  24 September 2020 | Open Access

  Inducible EphA4 knockout causes motor deficits in young mice and is not protective in the SOD1^G93A mouse model of ALS

  • Sara L. Dominguez
  • , Timothy Earr
  •  & Jesse E. Hanson

• Article
  23 September 2020 | Open Access

  The 6-min walk test as a new outcome measure in Amyotrophic lateral sclerosis

  • Massimo Russo
  • , Christian Lunetta
  •  & Sonia Messina

• Article
  15 September 2020 | Open Access

  Predictive factors for prognosis after gastrostomy placement in routine non-invasive ventilation users ALS patients

  • Adèle Hesters
  • , Maria del Mar Amador
  •  & Gaëlle Bruneteau

• Article
  30 July 2020 | Open Access

  Functional fine-mapping of noncoding risk variants in amyotrophic lateral sclerosis utilizing convolutional neural network

  • Ali Yousefian-Jazi
  • , Min Kyung Sung
  •  & Jinwook Choi

• Article
  17 July 2020 | Open Access

  Stimulus modality influences session-to-session transfer of training effects in auditory and tactile streaming-based P300 brain–computer interfaces

  • P. Ziebell
  • , J. Stümpfig
  •  & S. Halder

• Article
  16 July 2020 | Open Access

  Proteomics analysis of FUS mutant human motoneurons reveals altered regulation of cytoskeleton and other ALS-linked proteins via 3′UTR binding

  • Maria Giovanna Garone
  • , Vincenzo Alfano
  •  & Alessandro Rosa